Welcome to the Flor lab!

2016
 

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Molecular and Cellular Neurobiology & -pharmacology

The Flor laboratory works on the role of Metabotropic Glutamate Receptors (mGluRs, the G protein-coupled receptors for the mammalian main excitatory neurotransmitter L-glutamate) in conditions related to Chronic Stress, such as Anxiety, Depression and Substance Abuse.



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The main hypotheses:

Receptor subtype
Potential future applications for subtype-selective modulatory drugs
mGluR1
?
mGluR2/3
Schizophrenia, Anxiety, Depression …
mGluR4
Parkinson‘s Disease
mGluR5
Anxiety, Parkinson‘s, GERD, Migraine …
mGluR6
Night-blindness (?)
mGluR7
Anxiety, PTSD, Depression, Addiction
mGluR8
?

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