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2008-2010

Bartlang, Manuela Germany
Farzana, Fatima Pakistan
Guo, Da China
Hasler, Daniele Italy
Koszinowski, Sophie Germany
Kraus, Dominik Germany
Li, Zhang China
Liu, Wenrui China
Naik, Roshan Ratnakar India
Dr. Nagesh, C. Shanbhag India
Rotheneichner, Peter Germany
Seide, Christina Germany
Stindl, Julia Germany
Zunhammer, Matthias Germany

 

Bartlang, Manuela

Bartlang

City and country of origin:
Olching, Germany

Educational background:

  • Bachelor of Science in Biology,
    University of Regensburg
  • International Master's Programme in Experimental
    and Clinical Neurosciences (until now)

 

 

Main scientific interests
Neurodegenerative diseases, Psychology

Project Internships

1) Does the daytime of repeated stressor exposure influence the diurnal rhythmicity in male mice?
Supervisors: Prof Inga Neumann, Dr Stefan Reber; Prof Charlotte Förster, Dr Corinna Wühlbeck, University of Regensburg

2) Role of the circadian clock in response to psychosocial stress
Supervisor: Dr Gabriella Lundkvist, Karolinska Institutet in Stockholm

3) CD4+ FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo
Supervisor: Dr Oliver Grauer, University of Regensburg

Master project
Master project Title:
Does the daytime of repeated stressor exposure influence the diurnal rhythmicity in male mice?
Supervisors: Prof Inga Neumann, Dr Stefan Reber; Prof Charlotte Förster, Dr. Taishi Yoshii, University of Regensburg

Future Plans and objectives
Get my Master in Neuroscience; Complete my Diploma in Biology

 

Farzana, Fatima

Farzana

City and country of origin:
Islamabad, Pakistan

Educational background:

  • Bachelor of Life Science,
    National University of Singapore
  • Major: Molecular and Cell Biology Minor: Analytical Chemistry
  • International Master's Programme in Experimental
    and Clinical Neurosciences


Main scientific interests

  • Brain and brain functions – thinking, intuition and sixth sense
  • Human behavior and how brain affects human behavior
  • Brain and nervous system diseases

Project Internships

1) Influence of single nucleotide polymorphisms on the transcriptional activity of the promoter of HTRA1, a candidate gene for involvement in AMD pathogenesis*
Supervisors: Dr. Bernhard Weber and Dr. Ulrike Friedrich

2) Solutions for quantitative analytical problems in patients treated with a combination of risperidone and olanzapine*
Prof. Dr. Dr. Ekkehard Haen

Future Plans and objectives
Diseases and disorders of the nervous system and mental diseases as well as higher functions of the brain interests me deeply.I wish to conduct research on the interface of research and medicine, such that the output of my research has a direct impact in the solution of neurodegenerative diseases.

Publications

Erik Arner, Ellen Kindlund, Daniel Nilsson, Fatima Farzana, Marcela Ferella, Martti T Tammi, Bjorn Andersson. Database of Trypanosoma cruzi repeated genes: 20.000 novel coding sequences/ protein variants. BMC Genomics 2007, 8:391

 

Guo, Da

Guo, Da City and country of origin:
Changchun City, China

Educational background:

  • Bachelor of Biology,
    Xiamen University
  • International Master's Programme in Experimental
    and Clinical Neurosciences (until now)

Main scientific interests

Mirror Neurons and Neural Regeneration

Project Internships

1. Neurotrophic effects of norrin on cultured retinal ganglion cells
Supervisors: Prof. Ernst Tamm and Dr. Andears Ohlmann
University of Regensburg

2. Transcranial magnetic stimulation in patients with lumbosacral radiculopathy
Supervisors: Prof. Wilhelm Schulte-Mattler and MD Jose Angel G. Victores
Bezirksklinikum Regensburg

3. Characterisation of apoptotic signal transduction pathways in the β-bungarotoxin model of neuronal degeneration
Supervisors: Prof. Olaf Strauß
Universitätsklinikum Regensburg

Master project

Title: Characterisation of apoptotic signal transduction pathways in the β-bungarotoxin model of neuronal degeneration

The effect of the highly toxic β-bungarotoxin (β-BuTx), a component of the venom of the taiwanesian banded krait (Bungarus fasciatus), is well established model for apoptotic cell death in neuronal degeneration. β-BuTx consists of a subunit A displaying Ca2+ -dependent phospholipase A2 (PLA2) activity and a subunit B, which binds to voltage dependent K+ channels leading to subsequent internalization of β-BuTx. Interaction of β-BuTx with potassium channels initiates downstream events which include decomposition of the cell membrane phospholipids and adversely affect neurotransmitter release, finally inducing caspase-independent apoptosis selectively in neuron.

The aim of this study is to describe the mechanisms underlying the activation of ion channels in order to define new components of these yet not completely understood signaling cascades.

Supervisor: Prof. Olaf Strauß
Universitätsklinikum Regensburg

Future Plans and objectives
PhD in Neurosciences

 

Hasler, Daniele

Hasler, Daniele City and country of origin:
Rome, Italy

Educational background:

  • Bachelor of Science in Biology,
    University of Regensburg
  • International Master's Programme in Experimental
    and Clinical Neurosciences (until now)

Main scientific interests

Neurodegenerative diseases, their molecular mechanism, psychopathological consequences and therapies

 

Koszinowski, Sophie

Koszinowski City and country of origin:
Regensburg, Germany

Educational background:

  • Bachelor of Science in Biology,
    University of Regensburg
  • International Master's Programme in Experimental
    and Clinical Neurosciences (until now)

Main scientific interests
I am looking forward to the clinical part of the ECN-programme

Project Internships

1) Oxytocin induces translocation of phosphorylated ERK from the cytoplasm to the nucleus - Implications for anxiety-like behaviour?
Supervisors: Prof Dr. Inga Neumann; Dr. Erwin van den Burg
University of Regensburg

2) Effects of combined temporal and prefrontal rTMS-treatment on patients with chronic tinnitus
Supervisors: Dr. Michael Landgrebe, Dr. Berthold Langguth
University of Regensburg

3) 1. Virus-based targeting of Oxytocin neurons in the Paraventricular and the Supraoptic nuclei of the Hypothalamus in pregnant rats
2. Activation of TORC2 expression in the hypothalamic magnocellular neurons upon acute osmotic stimulation in rats

Supervisors: Prof Dr. Peter Seeburg, Dr. Valery Grinevich
Max Planck Institute Heidelberg

Master project

Title: Anxiolytic actions of Oxytocin in the Paraventricular Nucleus of the Hypothalamus - focus on gene regulation and CRH connectivity

 

Kraus, Dominik

KrausCity and country of origin:
Sulzbach-Rosenberg, Germany

Educational background:

  • Bachelor of Science in Biology,
    University of Regensburg
  • International Master's Programme in Experimental
    and Clinical Neurosciences

 

 

Main scientific interests

  • Genetics & the molecular background of the nervous system.
  • Research on stem cells to develop therapies for different diseases.

Future Plans and objectives
Finish the ECN-Programme successfully. Complete my Diploma in Biology. Start PhD studies.

 

Li, Zhang

Li, ZhangCity and country of origin:
Changchun, China

Educational background:

  • Bachelor of Science in Biotechnology,
    Huaqiao University
  • International Master's Programme in Experimental
    and Clinical Neurosciences

 

 

Main scientific interests

  • Higher cognitive functions like learning, memory,emotion.
  • Mind or brain disorders and syndromes like Huntington’s and Parkinson’s disease.

Project Internships

1) Audio-visual integration with exogenous spatial cues examined by fMRI
Supervisors: Prof Mark Greenlee; Dr. Anton Beer
University of Regensburg

2) Involvement of a novel neuropeptide, Ion transport peptide, in Drosophila’s circadian clock
Supervisors: Prof. Charlotte Foerster; Dr Taishi Yoshii
University of Regensburg

3) Study the relationship between frataxin and the Insulin Receptor Signaling pathway
Supervisors: Prof. Stephan Schneuwly; Dr. Juan Navarro
University of Regensburg

Master project

Title: The Analysis of mitochodria pathway in Parkinson's Disease by alpha-synuclein Drosophila
Supervision: Prof. Stephan Schneuwly; Dr. Juan Navarro, Dr. Jose Botella-Munoz,
University of Regensburg

Future Plans and objectives:
PhD in Neurosciences. Research in an excellent neuroscience research institute.

 

Liu, Wenrui

Liu WenruiCity and country of origin:
Kunming, China

Educational background:

  • Bachelor of Science in Biotechnology,
    Sichuan University, China
  • International Master's Programme in Experimental
    and Clinical Neurosciences

Main scientific interests
Neuroscience, psychology

Project Internships

1.Decisions about human faces – visual psychophysics and functional imaging experiments-
Supervisors: Dr. Gyula Kovacs, Prof. Dr. Mark Greenlee

Future Plans and objectives:
After graduated, I will go forward to PhD study in one of my interested areas and have my
scientific career in Psychology and Neurosciences

Publications
Studies on the treatment of polluted water from aquaculture with photosynthetic bacteria.
Reservoir Fisheries, ISSN 1003-1278(2006)02-0070-03, P.R. China

 

Naik, Roshan Ratnakar

Naik, Roshan RatnakarCity and country of origin:
Goa, India

Educational background:

  • M. Sc. in Marine Biotechnology,
    Goa University, India
  • International Master's Programme in Experimental
    and Clinical Neurosciences

 

 

Main scientific interests

Brain plasticity and lifespan ontogeny are my primary research interest, slight disruption of the physico-chemical balance in our brain leads to mental disorders and its dysfunction, which is my second topic of interest.

Project Internships

1. Mitochondrial role and cell death in a Drosophila model of Parkinson’s disease.
Supervisors: Dr. Juan A. Navarro, Prof. Dr. Stephan Schneuwly.
University of Regensburg.

2. Effects of angiotension on retinal pigment epithelium.
Supervisor: Prof. Dr. Olaf Strauss.
University of Regensburg.

3. To identify genetic polymorphisms underlying anxiolytic effects of NPS administration to HAB and LAB rats.
Supervisors: Dr. Ludwig Czibere, Prof. Dr. Rainer Landgraf.
Max Planck Institute of Psychiatry, Munich.

Master project

Master project title: To identify genetic polymorphisms underlying anxiolytic effects of NPS administration to HAB and LAB rats (continuation of 3rd project practicum).

Aim of Study:
Behavior is shaped by a variety of genetic and epigenetic mechanisms, including those underlying anxiety and fear. Neuropeptides are ideal candidates to be involved in the regulation of emotional facets as they are released within the brain and act as neuromodulators/neurotransmitters (Landgraf, 2001). A variety of approaches have been used to reveal the physiological involvement of neuropeptides in anxiety-related behavior, including those focused on behavioral effects of neuropeptides and, vice versa, the influence of behavioral phenomena on intracerebral neuropeptides.
Neuropeptide S (NPS) is a newly identified transmitter that modulates arousal and fear responses. NPS activates Neuropeptide S receptor (NPSR1) that is expressed throughout the central nervous system, including brain centers that regulate sleep/wakefulness and anxiety. A number of NPSR1 single nucleotide polymorphisms (SNPs) in humnans have been linked to susceptibility to inflammatory bowel disease and asthma.

Based on behavioral and neuroendocrine data obtained from proper animal models, the neurobiological and genetic analyses of anxiety and fear will provide the prerequisites to develop novel and more causal therapeutic strategies for anxiety disorders. Thus the aim of my study is to identify genetic polymorphisms underlying anxiolytic effects of NPS administration to HAB and LAB rats.

Future Plans and objectives:
In future, I plan to utilize various tools & techniques at an interdisciplinary level to decode the mystery of the master mind, “The Brain”.

 

Dr. Nagesh, C. Shanbhag

Dr. NageshCity and country of origin:
Sirsi, Karnataka, India

Educational background:

  • MBBS
    Bachelor of Medicine & Bachelor of Surgery,
    Goa Medical College, Bambolim-Goa (2001-2007)
  • International Master's Programme in Experimental
    and Clinical Neurosciences

 

Main scientific interests

  • Mechanisms of adult neurogenesis and in brain injury
  • Stem cell therapy in neurological disorders (like stroke, spinal cord injury, TLE)
  • Axonal regeneration; gene therapy in regeneration
  • Neuronal plasticity to environmental cues.

Project Internships

1) Dr Norbert Weidner, Department of Neurology
- OLIGODENDROGLIAL DIFFERENTIATION IN MOUSE and RAT NEURAL PROGENITOR CELLS SEEDED INTO A 3-DIMENSIONAL CELL CULTURE SYSTEM.

2) Dr.Felix Schlachetzki, Department of Neurology
Investigation of the expression profile of the VEGF receptor following ischemia/reperfusion in an immortalized human cerebral endothelial cell line. An in-vitro study.

Future Plans and objectives:
Neurosurgery residency programme; MD/PhD in Medical Neurosciences

Publications

Nagesh C Shanbhag, Hippocampus: A memorable Lesson to be Learnt (2008)
Electronic Journal of Biology, Vol.4, no.2, pages 47-58. Review.

 

Rotheneichner, Peter

RotheneichnerCity and country of origin:
Eggenfelden, Germany

Educational background:

  • Bachelor of Science in Biology, University of Regensburg
  • International Master's Programme in Experimental
    and Clinical Neurosciences

Main scientific interests
Developing new drugs for neuronal diseases.

Project Internships

1. Projekt: Regulatory elements of doublecortin expression and neuronal development
Supervisors: Prof Ludwig Aigner, Dr. Sébastien Couillard-Despres
Department of Neurology, University of Regensburg

2. Projekt: Monitoring of neurogenesis during EAE - Part II
Supervisors: Prof Dr. Ingo Kleiter
Department of Neurology, University of Regensburg

3. Projekt: Analysis of genes involved in neuronal development and plasticity in a model of rheumatoid arthritis
Supervisors: Prof Ludwig Aigner, Dr. Sébastien Couillard-Despres
Department of Neurology, University of Regensburg

Future Plans and objectives:
PhD in Neurosciences, set up a Company

 

Seide, Christina

SeideCity and country of origin:
Bad Segeberg, Germany

Educational background:

  • Bachelor of Science in Molecular Medicine, University of Ulm, Germany (2005-2008)
  • International Master's Programme in Experimental
    and Clinical Neurosciences (until now)

Main scientific interests

Derived from my background of molecular medicine I am very much interested in molecular and clinical neurosciences. I am very eager to learn more about the phsyiological processes underlying learning, conciousness and memory and their pathological changes resulting in neurodegenerative diseases. Especially genetics and genetherapy are a fascinating field, the techniques of which I would like to adopt and apply in the neurosciences in order to contribute to the development of new medical treatments.

However, during my studies in Regensburg I got to know more about brain imaging techniques and current psychological questions, the research of which is also becoming increasingly attractive for me.

 

Stindl, Julia

StindlCity and country of origin:
Augsburg, Germany

Educational background:

  • Bachelor of Science in Biology, University of Regensburg
  • International Master's Programme in Experimental
    and Clinical Neurosciences (until now)

Main scientific interests

In generall my interests are the molecular background behind diverese neurological diseases. Especially the molecular mechanisms behind synaptic plasticity, synaptogenesis and -degeneration as well as the molecular properties of prae- and postsynaptic structures, their pathologies and resulting diseases attract my attention. Furthermore learning and memory consolidation with main focus on the chemical synapse are an interesting field of research for me.

Project Internships

Expression and localization of different variants of ARMS2, a gene strongly associated with AMD pathogenesis, in mammalian cell lines
Supervision: Dr. Ulrike Friedrich, Prof. Dr. Berhard Weber
Institute of Human Genetics, University of Regensburg

 

Zunhammer, Matthias

ZunhammerCity and country of origin:
Traunstein, Germany

Educational background:

  • Bachelor of Science in Biology, University of Regensburg
  • Two semesters at the University of Colorado at Boulder

Main scientific interests
The neuroscience of pain

Project Internships

1. Effects of Deferriprone and Idebenone in Drosophila Models of Frataxin Deficiency
Supervisors: Dr. Juan Navarro, Prof. Dr. Stephan Schneuwli
University of Regensburg

2. Modulation of Temperature and Pain Sensitivity by rtMS of the Cerebellum
Supervisor: Dr. Berthold Langguth
University of Regensburg

3. Pain Matrix Activity in Irritable Bowel Syndrome
Supervisors: Dr. Katharina Rosengarth, Prof. Dr. Peter Eichhammer, Prof. Dr. Mark Greenlee
University of Regensburg

Master project: Pain Matrix Activity in Irritable Bowel Syndrome

Aim of the study:
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal condition which is strongly influenced by psychosocial factors. In this study, we assess differences in central processing of painful heat stimuli in IBS patients by functional Magnetic Resonance Imaging (fMRI). Hereby, we focus on brain regions also involved in processing of aversive social stimuli, as the amygdala, insula and the anterior cingulate cortex. This study addresses the question, if there are differences in responsivity and/or baseline activity in these regions.

Supervisors: Dr. Katharina Rosengarth, Prof. Dr. Peter Eichhammer, Prof. Dr. Mark Greenlee
Dept. of Psychiatry, Dept. of Experimental Psychology, University of Regensburg

Future Plans and objectives:
PhD in NEUROSCIENCES

Publications

Ehringer, M. A., Hoft, N. R., & Zunhammer, M. (2009). Reduced alcohol consumption in mice with access to a running wheel. Alcohol 43(6), 443-52