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2006-2008

Chiu, Wei-Hua Taiwan
Chiucu, Andrei Romania
Dinnbier, Matthias Germany
Ernst, Wolfgang Germany
Heckel, Andreas Germany
Karl, Alexandra Germany
Konstandin, Nicola Germany
Marxreiter, Franz Germany
Nafees, Ahmad Pakistan
Nyuyki, Kewir Cameroon
Pilsl, Anna Germany
Sinning, Anne Germany
Wagner, Katrin Germany

 

Chiu, Wei-Hua

Chiu, Wei-Hua

City and country of origin: Kaohsiung, Taiwan (R.O.C.)
Educational background:
Physical Therapy, National Yang-Ming University

International Master's Programme: Experimental and Clinical Neurosciences

Email

Main scientific interest:
I’m interested in the neurogenesis and neuroinflammation in the normal or pathological environment

Project Practicums:

  • Oxidative stress in a Drosophila model of Friedreich’s ataxia and new model of RNAi-mediated suppression of frataxin
    Supervision: Dr. Juan Navarro and Prof. S. Schneuwly
    Department of Developmental Biology, Institute of Zoology, University of Regensburg
  • Does the Secretory leukocyte protease inhibitor” influences the proliferation or maturation of oligodendroglia cell lines?
    Supervision: Dr. Andre Mueller and Dr. A. Steinbrecher
    Department of Neurology, University of Regensburg
  • Cloning and Expressing the T cell receptors of Myasthensia Gravis patients on hybridoma cells
    Supervision: Dr. K. Dornmair and Prof. H. Wekerle
    Department of Neuroimmunology, Max-Planck Institute, Neurobiologyp

Master project

  • Title:"Expression analysis and functional analysis of doublecortin-like molecules in neuronal stem and progenitor cells."
  • Aim of the study: The project is to analyse the expression of doublecortin-like proteins in neuronal stem and progenitor cells and to investigate their function in these cells.
  • Supervision: Dr. S. Couillard-Despres and Prof. L.Aigner Department of Neurology

Chiucu, Andrei

no portrait yet!

City and country of origin: Calarasi, Romania
Educational background:
Faculty of General Medicine, University of Medicine and Pharmacy „Carol Davila“, Bucharest, Romania

International Master's Programme: Experimental and Clinical Neurosciences

Email

Main scientific interest:
I’m interested in the neurogenesis and neuroinflammation in the normal or pathological environment.

Project Practicums:

  • Phenotype analysis of WDR36 knockout mice
    Supervision: Prof. Dr. Ernst Tamm
    Human Anatomy and Embryology University of Regensburg
  • Isolated brain perfusion model
    Supervision: Dr. Felix Schlachetzki
    Department of Neurology, University of Regensburg
  • Evaluation of the efficiency of the Human Caspase3 Ab in Drosophila embryos
    Supervision: Prof. Stefan Schneuwly
    Department of Developmental Biology, Institute of Zoology, University of Regensburg

 

Dinnbier, Matthias

Chiu, Wei-Hua

City and country of origin:
Regensburg, Germany

Educational background:
First Diploma in Psychology, University of Regensburg, Germany

International Master's Programme
Experimental and Clinical Neurosciences

Main scientific interest:

  • Human Sensory Processes (Visual Perception, Object Perception, Multisensory Processes)
  • Higher Cognitive Functions (Attention, Learning, Memory)

Project Practicums

  • The Influence of Mood on the Recognition of Emotions
    Supervision: Dr. Alexa Veenema, Prof. Dr. Mark Greenlee
    Department of Behavioral Neuroendocrinology and Department of Experimental Psychology, University of Regensburg
  • Segmentation of Simple Objects: Serial Processing or Holistic Perception?
    Supervision: Drs. Ilia Korjoukov, Prof. Dr. Pieter R. Roelfsema
    Vision Cognition Group, Netherlands Institute of Neuroscience, Royal Dutch Academy of Sciences,
    Amsterdam, The Netherlands
  • Serial Processing Effects in Mental Tracing of Simple Prolonged Objects
    Supervision: Drs. Ilia Korjoukov, Prof. Dr. Pieter R. Roelfsema
    Vision Cognition Group, Netherlands Institute of Neuroscience, Royal Dutch Academy of Sciences,
    Amsterdam, The Netherlands

Future Plans and objectives

  • University Diploma in Psychology
  • Master of Science in Neurosciences
  • Doctoral Studies in Psychology or Neurosciences
  • Scientific Career in Psychology and Neurosciences

Ernst, Wolfgang

no portrait yet!

City and country of origin:
Ruhpolding, Germany

Educational background:

  • 1992-2001, Chiemgau
    Gymnasium Traunstein
  • since 2002, Biology,
    University of Regensburg
  • International Master's Programme:
    Experimental and Clinical Neurosciences

Main scientific interest:

Research on stem cells as therapy for certain diseases

Project Practicums:

  • Expression analysis of doublecortin family members in adult neural stem cells
    Supervision: Dr. Sebastien Couillard-Després
  • Neurodegeneration in the PNS of Drosophila and Expression of TOR in wt and frataxin overexpressing flies
    Supervision: Dr. Juan Navarro, Prof. Dr. Stefan Schneuwl
    Department of developmental Biology, Institute of Zoology, University of Regensburg
  • TYROBP promoter study in Macrophages
    Supervision: Dr. Thomas Langmann
    Human Genetics, University of Regensburg

Master project

Title: Molecular characterization of dental precursor cells during retinal differentiation in vitro
Supervision: Dr. Christian Morsczeck, Human Genetics, University of Regensburg

Heckel, Andreas

Andreas Heckel

City and Country of origin:
Regensburg, Germany

Educational background:
Medical Program, University of Regensburg

International Master's Programme
'Experimental and Clinical Neurosciences'

 

 

Main scientific interest

  • Illusions
  • Multisensory Integration
  • Computational Neuroscience

Project Practicums

Multisensory Integration
Supervision: Prof. Dr. Mark Greenlee
Department of Experimental Psychology, University of Regensburg

Compensation of fixational Eye Movements
Supervision: Prof. Dr. Mark Greenlee
Department of Experimental Psychology, University of Regensburg

Flow parsing Hypothesis
Supervision: Department of Neural Information Processing, Ulm

Master project

Title: Mulitsensory Integration – a neurophysiological Model
Aim of the study:
We test a recent model of auditory-visual integration and segregation. Task-dependent superposition and segregation of neural activity is described by modeling the functioning of multimodal neurons
Supervision: Prof. Dr. Mark Greenlee
Department of Experimental Psychology, University of Regensburg

Karl, Alexandra

Alexandra Karl

City and Country of origin:
Munich, Germany

Educational background:
Biology Diploma, University of Regensburg

International Master's Programme
'Experimental and Clinical Neurosciences'

Main scientific interest

  • Adult neurogenesis

Project Practicums

Influence of a dopamine D3 receptor agonists on adult hippocampal neurogenesis
Supervision: Dr. Beate Winner, Prof. Dr. Jürgen Winkler
Department of Neurology, University of Regensburg

Influence of the PI3 kinase signalling pathway on proliferation of adult neural stem cells
Supervision: Dr. Chichung Lie
Department of Developmental Biology, GSF, Munich

Influence of different transcription factors on neurite outgrowth in a cell culture of cerebellar granule neurons
Supervision: Dr. Armin Blesch
Department of Neurosciences, University of California, San Diego, USA

Master project

Title: Influence of the PI3Kinase / mTOR signaling pathway on adult neural stem cells

Future Plans and objectives:
PhD

Konstandin, Nikola

no profile picture yet!

City and Country of origin:
Regensburg, Germany

Educational background:
Biology Diploma, University of Regensburg

International Master's Programme
'Experimental and Clinical Neurosciences'

 

 

Main scientific interest

I’m interested in molecular biology, especially in the field of neuroscience. Focusing on genetics.

Project Practicums

Effects of chronic stress on late pregnancy and lactation in rats
Supervision: Dr. David Slattery, Prof. Dr. Inga Neumann
Department of Molecular and Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg

Investigations on VMD2 –Immortalization of primary cells
Supervision: Dr. Florian Rauscher, Prof. Dr. Bernhard Weber
Institute of Human Genetics, University of Regensburg

Effects of Single Nucleotide Polymorphism RS2070951 on Human Mineralcorticoid Receptor A and B expression
Supervision: Nienke van Leeuwen, Dr. Roel de Rijk, Prof. Dr. Ron de Kloet
Division of Medical Pharmacology. Gorlaeus Laboratory, University of Leiden, The Netherlands

Master project

Title: Molecular and phenotypic characterization of a Bestrophin deficient mouse model
Supervision: Prof. Dr. Bernhard Weber
Institute of Human Genetics, University Regensburg

Future Plans and objectives

The nearest future plans are to finish the ECN program successfully and afterwards starting my PHD. I think doing the PHD abroad would be nice.

Marxreiter, Franz

Franz Marxreitner

City and Country of origin:
Regensburg, Germany

Educational background:
Medicine, University of Regensburg

International Master's Programme
'Experimental and Clinical Neurosciences'

Email: franz.marxreiter@gmail.com

 

Main scientific interest:
Adult neurogenesis, neuronal stem cells, neurodegenerative diseases

Project Practicums

1) Adult olfactory bulb neurogenesis in an alpha-synuclein expressing mouse model
Supervisors: Prof Jürgen Winkler; Dr. Beate Winner
University of Regensburg

2) Regulation of DCX expression by miRNA's in embryonic neuronal progenitor cells
Supervisors: Prof Ludwig Aigner, Dr. Sébastien Couillard-Despres
University of Regensburg

3) Evaluation of ß-catenin mediated regulation of Sox2
Supervisors: Dr. Chichung Lie, Dr. Lucia Berti
Helmholtz Zentrum München

Master project

Title: A30P alpha-synuclein regulates adult olfactory bulb neurogenesis

Aim of the study: Hyposmia is an important and early premotor symptom in Parkinson’s disease (PD). In PD brains, alpha-synuclein pathology is present in the olfactory bulb (OB). In addition, the OB is an active region of adult neurogenesis, where newly generated neurons physiologically integrate. While accumulation of wildtype alpha-synuclein is one of the pathogenic hallmarks of non-genetic forms of PD, the A30P alpha-synuclein mutation results in an earlier disease onset. Recent work indicated that olfactory neurogenesis is decreased in adult transgenic models of synucleinopathies due to a decreased survival of newly generated neurons. Nothing so far is known about the effects of A30P alpha-synuclein on adult neurogenesis or if halting expression of alpha-synuclein could reverse the previously described decrease in adult neurogenesis. This lead to the idea to study adult neurogenesis in the subventricular zone (SVZ)/OB system in a tetracycline suppressive (tet-off) transgenic model, expressing human mutant A30P alpha-synuclein under the control of the Calcium/Calmodulin dependent Kinase 2 alpha (CaMK II) promoter which allows transient suppression of the alpha-synuclein transgene. This project can (1 )provide insights into mechanisms of early cellular dysfunction induced by alpha-synuclein, (2) foster the understanding of alpha-synuclein mediated reduction of cellular plasticity. Both points might be crucial events in the pathogenesis of PD and in turn are promissing tools for future therapeutic strategies.

Supervision: Prof. Jürgen Winkler, Dr. Beate Winner
Department of Neurology, University of Regensburg

Nafees, Ahmad

Chiu, Wei-Hua

City and Country of origin:
Gujranwala, Pakistan

Educational background:
M.Phil (Molecular Biology) CEMB
University of the Punjab, Lahore Pakistan

M.Sc.(Zoology) Govt. College
University Lahore, Pakistan

International Master's Programme
'Experimental and Clinical Neurosciences'

Main scientific interest

Human Genetics, Molecular Biology, Biomedical

Project Practicums

Development of animal model for Human autosomal dominant Retinitis Pigmentosa
Supervision: Dr. Juan Navaro, Prof. Dr. Stefan Schneuwly
Department of Developmental Biology, Institute of Zoology, University of Regensburg

Effect of Chronic Stress on Physiological and Molecular adaptations in virgin and pregnant rats
Supervision: Dr. David Slattery, Prof. Dr. Inga Neumann
Department of Molecular an Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg

Screening for Polymorphisms in CRH gene
Supervision: Prof. Dr. Rainer Landgraf
Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany

Master project

Title:
Screening for Genetic factors responsible for Thalassemia Intermedia in Pakistan
Supervision: Dr. Shaheen N. Khan
National Center of Excellence in Molecular Biology, University of the Punjab, Lahore Pakistan

Title:
Genotyping of the anxiety related genes
Supervision: Prof. Dr. Rainer Landgraf
Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany

Future Plans and objectives

To be a researcher to study the diseased genes and their interaction with the environment

Current position: PhD-student

Title:
Functional analysis of the Pitx3 signalling in mutant mouse aphakia: a model of hereditary micropthalmie and Parkinson disease
Supervisor: Prof. Dr. Joachen Graw
Institute: Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health
Neuherberg, Germany

Nyuyki, Kewir

Kewir Nyuyki

City and Country of origin:
Sop, Cameroon

Educational background:

  • CGCE; O_level, Government Bilingual High School
    Jakiri, Cameroon
  • CGCE; A_level, Saint Augustine's College
    Kumbo, Cameroon
  • BSc. Biochemistry; Medical laboratory Technology Buea University, Buea, Cameroon

 

International Master's Programme
'Experimental and Clinical Neurosciences'

Main scientific interest
I look up to getting an insight of the neurobiological mechanisms which underlie human behaviour (anxiety/depression) and why not thee pathological transits involving neurodegenerative disorders

Project Practicums

Effects of Colour Perception on Auditory and Somato sensory perception
Supervision: Dr. B. Langguth, Dr. M. Landgrebe, Dr. P. Eichhammer
Department for Psychiatry and Psychotherapy, University of Regensburg

Expression Analysis of Antioxidant Enzymes in Transgenic Drosophila melanogaster
Supervision: Dr. Juan A. Navarro, Prof Dr. S. Schneuwly
Department of Developmental Biology, Institute of Zoology, University of Regensburg

Brain Oyxtocin Mediated Effects of mating on anxiety related behavior in female Wistar rats
Supervision: Martin Waldherr, Prof. Dr. Inga Neumann
Department of Molecular an Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg

Master project

Title:
Brain Oxytocin mediated effects of mating on anxiety related behavior in genetically modified HAB/LAB male rats

Aim of the study: Sexual activity is a physiological stimuli, like any other stimuli (lactation, parturition), triggering release of the neuropeptide Oxytocin from the magnocellular neurons of the hypothalamic Supraoptic Nucleus(SON) and Paraventricular Nucleus(PVN). The anxiolytic receptor mediated effects of this neuropeptide have been shown in males (PVN and Central Amygdala) after mating (Waldherr and Neumann, unpublished) but nothing is known so far, about its effects on inborn genetically modified rats. My interest then proceeds, with a keen attention in long term behavioural impacts.

Supervision: Prof. Dr. Inga Neumann
Department of Molecular an Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg

Future Plans and objectives

Behavioural Neuroendocrinology is an interesting branch of Neuroscience, relating daily actions/reactions with neurobiological mechanisms. Specializing as a behavioural Neuroscientist in the advanced academic ladder will be my point my interest. But as flexible as science can be, clinical neurosciences is another line of interest, as a lot of diseases are traced to be of neurobiological origin

Pilsl, Anna

Anna Pilsl

City and Country of origin:
Munich, Germany

Educational background:

  • Biology Diploma, University of Regensburg
  • Bachelor of Science in Biology
  • International Master's Programme
    'Experimental and Clinical Neurosciences'

Email: anna_pilsl@yahoo.de

 

Main scientific interest

Molecular Mechanisms involved in Neurodegenerative Diseases

Project Practicums

Molecular Analysis of Sorsby Fundus Dystrophy Mutation Timp3S156C
Supervision: Prof. Dr. Bernhard Weber
Institute of Human Genetics, University Hospital of Regensburg

Effects of Connective Tissue Growth Factor (CTGF) on Extracellular Matrix Composition
Supervision: Prof. Dr. Ernst Tamm
Institute of Human Anatomy, University of Regensburg

Identification of Tau-transgenic Zebrafish
Supervision: Prof. Dr. Christian Haass
Laboratory for Alzheimer's and Parkinson's Disease Research, Ludwig-Maximilians-University Munich

Master project

Title: “Establishment of a Transgenic Zebrafish Model to Study the Neuroprotective Activity of Parkin in vivo”

Aim of the study: Parkinson's disease (PD) is the most common movement disorder and the second most common neurodegenerative disease after Alzheimer's disease. The pathological hallmark of PD is a specific loss of dopaminergic neurons in the substantia nigra pars compacta, resulting in a variety of symptoms including rigidity, resting tremor, bradykinesia and postural instability. Only recently it has been discovered that, besides environmental factors, also genetic mutations play a major role in about 20% of all PD cases. One of the genes involved in PD, the parkin (PARK2) gene, encodes a 465 amino acid protein with an ubiquitin-like domain (UBL) at the N-terminus and a RING box close to the C-terminus. Parkin acts as an E3 ubiquitin ligase catalyzing the transfer of ubiquitin moieties to target proteins. Through activation of the NF-kB pathway, Parkin appears to be a potent neuroprotecting agent. Using the advantages of the zebrafish (Danio rerio) model system we now plan to assess Parkin´s neuroprotective capacity and biochemical function in a novel animal model.
For further information visit:
http://haass.web.med.uni-muenchen.de/Research/NBC/index.html

Supervision: Dr. Konstanze Winklhofer
Ludwig-Maximilians-University Munich, Department of Biochemistry

Sinning, Anne

Chiu, Wei-Hua

City and Country of origin:
Kassel, Germany

Educational background:

  • BSc. Molecular Biology, University of Mainz, Germany
  • International Master's Programme
    'Experimental and Clinical Neurosciences'

Main scientific interest

I am interested in physiological and especially electrophysiological properties of neurons enabling its unique and miscellaneous signaling within the brain and possible implications for various diseases

Project Practicums

Identification of Ca2+activated Cl--channels in epithelial cells: Bestrophin
Supervision: Dr. K. Kunzelmann
Department of Physiology, University of Regensburg

Connective Tissue Growth Factor and Glaucoma
Supervision: Prof. Dr. E. Tamm
Department of Anatomy and Embryology, University of Regensburg

Influence of intracellular calcium levels on circadian rhythms in mammals
Supervision: Dr. S. Michel
Department of Neurophysiology, University Medical Center Leiden, Leiden, The Netherlands

Master project

Title: Influence of membrane properties on expression of circadian rhythms in mammalian central pacemaker neurons

Aim of the study: The mammalian circadian clock is driven by a molecular machinery residing in central pacemaker neurons in a part of the hypothalamus known as the suprachiasmatic nucleus (SCN). Until recently, the role of membrane excitability for the circadian clock has been restricted to input and output. But there is increasing evidence that it is crucial for the maintenance of rhythmicity within the SCN. Aim of my master thesis is to obtain further insights into the of role calcium signaling and membrane excitability for the circadian rhythm in mammals.

Supervision: Dr. S. Michel
Department of Neurophysiology, University Medical Center Leiden, Leiden, The Netherlands

Future Plans and objectives
After a successful completion of my master thesis in Leiden I hope to perform a PhD thesis and enlarge my knowledge in the field of (electro-) physiology

Current position: PhD-student
Title: Functional analysis of anion exchangers in different transgene mouse models
Supervisor: Prof. Dr. C.A. Hübner
Institute: Institute of Clinical Chemistry, Clinic University Jena, Jena, Germany

Wagner, Katrin

Katrin Wagner

City and Country of origin:
Geraberg, Germany

Educational background:

  • Biology Diploma, University of Regensburg
  • International Master's Programme
    'Experimental and Clinical Neurosciences'

Main scientific interest

Neuroscience, Genetics

Project Practicums

Is the oxytocin-induced activation of ERK 1/2 pathway within the hypothalamus mediated by endocannabinoid receptor type 1?
Supervision: Dr. Annegret Blume, Prof. Dr. Inga Neumann
Department of Molecular and Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg

Molecular Characterization of Microglia Activation related to Retinal Degeneration
Supervision: Dr. Thomas Langmann
Institute of Human Genetics, University of Regensburg

The effects of prolactin on stress induced CRH expression
Supervision: Prof. Dr. Greti Aguilera
National Institutes of Health, Developmental Endocrinology Branch, NICHD, Bethesda, Maryland, USA

Master project

Title: Regulation of adult neural progenitor cell proliferation by stress-related molecules in vitro
Supervision: Prof. Dr. Ludwig Aigner
Department of Neurology, University Clinic of Regensburg