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Ausgewählte Veröffentlichungen
- Ettlinger, C. and Lehle, L. (1988) Auxin induces rapid changes
in phosphatidylinositol metabolites. Nature 331, 176 - 178.
- Te Heesen, S., Janetzky, B., Lehle, L. and Aebi,M. (1992) The
yeast WBP1 is essential for N-oligosaccharyltransferase in vivo and
in vivo. EMBO J. 11, 2071-2075.
- Te Heesen S., Knauer, R., Lehle.L. and Aebi, M. (1993) Yeast
Wbp1p and Swp1p form a protein complex essential for oligosaccharyltransferase
activity. EMBO J. 12, 279-284.
- Rohrmeier, T. and Lehle.L. (1993) WIP1, a wound inducible gene
from maize with homology to Bowman-Birk proteinase inhibitors. Plant
Mol. Biol. 22, 783-792.
- Knauer, R. and Lehle, L. (1994) The N-oligosaccharyltransferase
complex from yeast. FEBS Letters 344, 83-86.
- Knauer, R., Lehle, L. Hanefeld, F. and von Figura, K. (1994)
Normal N-oligosaccharyl transferase activity in fibroblasts from patients
with carbohydrate-deficient glycoprotein syndrome. J. Inher. Metab.
Dis. 17, 541 - 544.
- Lehle, L., Eiden, A., Lehnert, K., Haselbeck,T. and Kopetzki, E.
(1995) Glycoprotein biosynthesis in yeast: ngd29, a yeast mutant
allelic to och1 having a defect in outer chain formation. FEBS Letters
370, 41-45.
- Zufferey, R., Knauer, R., Burda, P., Stagljar, I., TeHeesen, S.,
Lehle, L and Aebi, M. (1995) STT3, a highly conserved protein required
for yeast oligosaccharyl transferase activity in vivo. EMBO J. 14, 4949-4960.
- Körner, C., Lehle, L. and von Figura, K. (1998) Abnormal synthesis
of mannose 1-phosphate derived carbohydrates in carbohydrate-deficient
glycoprotein syndrome type I fibroblasts with phosphomannomutase deficieny.
Glycobiology, 8, 165-172.
- Rothe, C. and Lehle, L. (1998): Sorting of invertase signal
peptide mutants in yeast dependent and independent on the signal-recognition
particle. Eur. J. Biochem. 252, 16-24.
- Körner, C., Knauer*, Lehle,.L. and von Figura, K. (1998) Carbohydrate
deficient glycoprotein syndrome type V: deficiency of Dol-P-Glc: Man9GlcNAc2-PP-Dol
glucosyltransferase. Proc. Natl. Acad. Sci. USA. 95, 13200-13205. *The
first two authors contributed equally to this study.
Reviews:
- Lehle, L., (1991) Phosphatidyl inositol metabolism and its
role in signal transduction in growing plants. Plant Mol. Biol. 15,
647 - 658.
- Lehle, L. and Tanner, W. (1995) Protein glycosylation in yeast.
In: Montreuil, J. Schachter, H. and Vliegenthart, J.F.G. (Eds.) Glycoproteins,
New Comprehensive Biochemistry, Vol. 29a, pp 475-509, Elsevier Science
- Knauer, R. and Lehle, L. (1999) The oligosaccharyltransferase
complex from yeast. Biochim. Biophys. Acta. 1426, 259-273
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