References of Prof. M. Thomm, Prof. R. Wirth, PD Dr. W. Hausner, Prof. R. Rachel and Dr. H. Huber.

Veröffentlichungen Prof. M. Thomm:

Publikationen zum Thema "Transkription":

Wettach, J., Gohl, H.P., Tschochner, H., Thomm, M.: Functional interaction of yeast and human TATA-binding proteins with an archaeal RNA polymerase and promoter. Proc. Natl. Acad. Sci. (U.S.A.) 92, 472-476 (1995).

Hausner, W. and Thomm, M.: The translation product of the presumptive Thermococcus celer TATA-binding Protein sequence is a transcription factor related in structure and function to Methanococcus Factor B. J. Biol. Chem. 270, 17649-17651 (1995).

Gohl, H.P., Gröndahl, B., Thomm, M.: Promoter recognition in archaea is mediated by transcription factors: Identification of aTFB from Methanococcus thermolithotrophicus as archaeal TATA-binding protein. Nucl. Acids Res. 23, 3837-3841 (1995).

Hethke, C., Geerling, Ans C. M., Hausner, W., de Vos, W. and Thomm, M.: A cell-free transcription system for the hyperthermophilic Archaeon Pyrococcus furiosus. Nucl. Acids Res. 24, 2369-2376 (1996).

Thomm, M.: Archaeal transcription factors and their role in transcription initiation. FEMS Microbiol. Rev. 18, 159-171 (1996).

Hausner, W., Wettach, J., Hethke, C. and Thomm, M.: Two Transcription Factors Related with the Eucaryal Transcription Factors TATA-binding Protein and Transcription Factor IIB Direct Promoter Recognition by an Archaeal RNA Polymerase. J. Biol. Chem. 271 30144-30148 (1996).

Roovers, M., Hethke, C., Lagrain, C., Thomm, M. and Glansdorff, N.: Enzymatic carbamoylation at high temperatures. I. Isolation of the gene encoding Pyrococcus furiosus ornithine carbamylase and study of its expression profile in vivo and in vitro. Eur. J. Biochem. 247, 1038-1045 (1997).

Soares, D., Dahlke, I, Li, W.-T., Sandman, K., Hethke, C., Thomm, M. and Reeve, J.N.: Archaeal histone stability, DNA binding, and transcription above 90 °C. Extremophiles 2, 75-81 (1998).

van der Oost, J., Schut, G., Kengen, S.W.M., Hagen, W.R., Thomm, M. and de Vos, W.: The Ferredoxin-dependent Conversion of Glyceraldehyde-3-phosphate in the Hyper-thermophilic Archaeon Pyrococcus furiosus Represents a Novel Site of Glycolytic Regulation. J. Biol. Chem. 273, 28149-28154 (1998).

Darcy, T., Hausner, W., Awery, D.E., Edwards, A. M. Thomm, M. and Reeve, J.N.: Methanobacterium thermoautotrophicum RNA Polymerase and Transcription in vitro. J. Bacteriol. 181, 424-429 (1999).

Voorhorst, W.G.B., Gueguen, Y., Schut, G., Geerling, A., Dahlke, I., Thomm, M., van der Oost, J. and de Vos, W.: Transcriptional Regulation in the Hyperthermophilic Archaeon Pyrococcus furiosus: Coordinated Expression of Divergently Transcribed Genes in Response to ß-Linked Glucose Polymers. J. Bacteriol. 181, 3777-3783 (1999).

Hethke, C., Bergerat, A., Hausner, W., Forterre, P. and Thomm, M. Cell-free transcription at 95 °C. Thermostability of transcriptional components and DNA topology requirements of Pyrococcus transcription. Genetics 152, 1325-1323 (1999).

Thomm. M. Transkriptionsmaschinerie der Archaea. Biospektrum 3, 179-185 (2000).

Bartlett, M.S., Thomm, M., and Geiduschek, E.P. The orientation of DNA in archaeal transcription initiation complex. Nature Struct. Biol. 7, 782-785 (2000).

Brinkman, A., Dahlke, I., Tuininga, J., Lammers, T., Dumay, V., de Heus, E., Lebink, J.H.G., Thomm, M., de Vos, W.M., and van der Oost, J. An Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus is negatively regulated. J. Biol.Chem. 275, 38160-38169 (2000).

Hausner, W., and Thomm, M. Events during initiation of archaeal transcription: open complex formation and dna-protein interactions. J. Bacteriol. 183, 3025-3031 (2001).

Thomsen, J., de Biase, A., Kaczanowski, S., Macario, A. J. L., Thomm, M., Zielenkiewicz, P., MacColl, R., and Conway de Macario, E. The Basal Transcription Factors TBP and TFB from the Mesophilic Archaeon Methanosarcina mazeii: Structure and Conformational Changes upon Interaction with Stress-gene Promoters. J. Mol. Biol. 309 (3), 589-603 (2001).

Dahlke, I., and Thomm, M. A Pyrococcus homologue of the Leucine-responsive regulatory protein, LrpA, inhibits transcription by abrogating RNA polymerase recruitment. Nucleic Acids Res. 30, 701-710 (2002).

Vierke, G., Engelmann, A., Hebbeln, C., and Thomm, M.: A novel archaeal transcriptional regulator of heat shock response. J. Biol. Chem. 278, 18-26 (2003).

Lee, S.-J., Engelmann, a., Horlacher, R., Qu, Q., Vierke, G., Hebbeln, C., Thomm, M., and Boos, W.: TrmB, a sugar-specific transcriptional regulator of the trehalose/maltose ABC transproter from the hyperthermophilic archaeon Thermococcus litoralis. J. Biol. Chem. 278, 983-990 (2003).

Spitalny, P., and Thomm, M. Analysis of the open region and of DNA-protein contacts of archaeal RNA polymerase transcription complexes during transition from initiation to elongation. J Biol Chem 278: 30497-30505 (2003).

Noon, K.R., Guymon, R., Crain, P.F., McCloskey, J.A., Thomm, M., Lim, J., and Cavicchioli, R.: Influence of temperature on tRNA modification in Archaea: Methanococcoides burtonii (optimum growth temperature [Topt], 23°C) and Stetteria hydrogenophila Topt, 95°C). J. Bacteriol. 185, 5483-5490 (2003).

Bartlett, M.S., Thomm, M., and Geiduschek, E.P.: Topography of the euryarchaeal transcription initiation complex. J. Biol. Chem. 279, 5894-5903 (2004).

Lee, S.J., Moulakakis, C., Hausner, W., Koning, S.M., Thomm, M., and Boos, W.: TrmB, a sugar sensing regulator of ABC transporter genes in Pyrococcus furiosus exhibits dual promoter specificity and is controlled by different inducers. Mol. Microbiol. 57, 1797-1807 (2005).

Goede, B., Naji, S., von Kampen, O., Ilg, K., and Thomm, M.: Protein-protein interactions in the archaeal transcriptional machinery: binding studies of isolated RNA polymerase subunits and transcription factors. J. Biol. Chem. 281, 30581-30591 (2006).

Thomm, M., and Hausner, W.: Transcriptional Mechanisms. In: Archaea: Evolution, Physiology and Molecular Biology. R. Garrett and H.-P. Klenk (eds.). Blackwell Publishing, Oxford, U.K., Chapter 16, 185-198 (2006).

Naji, S., Grünberg, S., and Thomm, M.: The RPB7 orthologue E’ is required for transcriptional activity of a reconstituted archaeal core enzyme at low temperatures and stimulates open complex formation”. J. Biol. Chem. 282, 11047-11057 (2007).

Thomm, M.: Transcription: Mechanism and Regulation. In: Archaea Mollecular and Cellular Biology. R. Cavicchioli (ed.). ASM Press, Washington DC, U.S.A., Chapter 6, 139-157 (2007).

Liu, W., Vierke, G., Wenke, A.-K., Thomm, M., and Ladenstein, R.: Crystal structure of the archaeal heat shock regulator from Pyrococcus furiosus: A molecular chimera representing eukaryal and bacterial features. J. Mol. Biol. 369, 474-488 (2007).

Lee S.J., Surma M., Seitz S., Hausner W., Thomm M., and Boos W.: Differential signal transduction via TrmB, a sugar sensing transcriptional repressor of Pyrococcus furiosus. Mol Microbiol. 64(6):1499-505 (2007).

Pisa, K.Y., Huber, H., Thomm, M., and Müller, V.: A sodium ion-dependent A1A0 ATP synthase from the hyperthermophilic archaeon Pyrococcus furiosus. FEBS J., 274, 3928-3938 (2007).

Lee, S.J., Surma, M., Seitz, S., Hausner, W., Thomm, M., and Boos, W.: Characterization of the TrmB-like protein, PF0124, a TGM-recognizing global transcriptional regulator of the hyperthermophilic archaeon Pyrococcus furiosus. Mol. Microbiol. 65(2), 305-318 (2007).

Grünberg, S., Bartlett, M.S., Naji, S., and Thomm, M.: Transcription factor E is a part of transcription elongation complexes. J. Biol. Chem. 282(49), 35482-35490 (2007).

Micorescu, M., Grünberg, S., Franke, A., Cramer, P., Thomm, M., and Bartlett, M.: Archaeal transcription: function of an alternative transcription factor B from Pyrococcus furiosus. Angenommen im J. Bacteriol. (2007).

Kusser, A. G., Bertero, M. G., Naji, S., Becker, T., Thomm, M., Beckmann, R., and Cramer, P.: Structure of an archaeal RNA polymerase. J. Mol. Biol. 376, 303-307 (2008).

Naji, S., Bertero, M.G., Spitalny, P., Cramer, P., and Thomm, M.: Structure-function analysis of the RNA polymerase cleft loops elucidates initial transcription, DNA unwinding, and RNA displacement. Nucl. Acids Res. 36, 676-687 (2008).

Spitalny, P., and Thomm, M.: A polymerase III-like reinitiation mechanism is operating in regulation of histone expression in Archaea. Mol. Microbiol. 67(5), 958-970 (2008).

Lee, S.-J., Surma, M., Hausner, W., Thomm, M., and Boos, W.: The role of TrmB and TrmB-like transcriptional regulators for sugar transport und metabolism in the hyperthermophilic archaeon Pyrococcus furiosus. Archives Microbiol. 190(3):247-56 (2008).

Lipscomb, G. L., Keese, A. M., Cowart, D. M., Schut, G. J., Thomm, M., Adams, M. W. W., and Scott, R. A.: SurR: A transcriptional activator and repressor contolling hydrogen and elemental sulfur metabolism in Pyrococcus furiosus. Mol. Microbiol. 71, 332-349 (2009).

Thomm, M., Reich, C., Grünberg, S., and Naji, S.: Mutational studies of archaeal RNA polymerase and analysis of hybrid polymerases. Biochem. Soc. Trans. 37, 18-22 (2009).

Reich, C., Zeller, M., Milkereit, P., Hausner, W., Cramer, P., Tschochner, H. and Thomm, M.: The archaeal RNA polymerase subunit P and the eukaryotic polymerase subunit Rpb12 are interchangeable in vivo and in vitro. Molecular Microbiology 71(4), 989-1002, (2009).

Kostrewa, D., Zeller, M. E., Armache, K.-J., Seizl, M., Leike, K., Thomm, M., and Cramer, P.: RNA polymerase II – TFIIB structure and mechanism of transcription initiation. Nature 462, 323-330 (2009). Nature doi:10.1038/nature08545 (2009).

Keese, A. M., Schut, G. J., Ouhammouch, M., Adams, M. W. W., and Thomm, M.: Genome wide identification of targets for the archaeal heat shock regulator Phr by cell free transcription of genomic DNA. J. Bacteriol.192, 1292-1298 (2010).

Grünberg, S., Reich, Ch., Zeller, M., Bartlett, M., and Thomm, M.: Rearrangement of the RNA polymerase subunit H and the lower jaw in archaeal elongation complexes. Nucl. Acids Res., 38, 1950-1963 (2010).

Waege, I., Schmid, G., Thumann, S., Thomm, M., and Hausner, W.: A shuttle vector based transformation system for Pyrococcus furiosus. Appl. Environ. Microbiol. 76, 3308-3313 (2010).

Thomm, M.: Die genetische Maschinerie der Archaea: Vorläufer und ein Modell für die Regulation der Genexpression in höheren Zellen“. In: Biologie für Einsteiger. O. Fritsche (ed.): Spektrum Akademischer Verlag Heidelberg, pp. 284-285 (2010).

Armache, J.P., Jarasch, A., Anger, A.M., Villa, E., Becker, T., Bhushan, S., Jossinet, F., Habeck, M., Dindar, G., Franckenberg, S., Marquez, V., Mielke, T., Thomm, M., Berninghausen, O., Beatrix, B., Soding, J., Westhof, E., Wilson, D.N., and Beckmann, R. Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5 Åresolution. Proc. Natl. Acad. Sci. U.S.A., 107, 19748-19753 (2010).

Armache, J.P., Jarasch, A., Anger, A.M., Villa, E., Becker, T., Bhushan, S., Jossinet, F., Habeck, M., Dindar, G., Franckenberg, S., Marquez, V., Mielke, T., Thomm, M., Berninghausen, O., Beatrix, B., Soding, J., Westhof, E., Wilson, D.N., and Beckmann, R. Localization of eukaryote-specific ribosomal proteins in a 5.5 Åcryo-EM map oft he 80S eukaryotic ribosome.. Proc. Natl. Acad. Sci. U.S.A., 107, 19754-19759 (2010).

Márquez, V., Fröhlich, T., Armache, J.-P., Sohmen, D., Dönhöfer, A., Mikolajka, A., Berninghausen, O., Thomm, M., Beckmann, R., Arnold, G.J., and Wilson, D.N.: Proteomic characterization of archaeal ribosomes reveals the presence of novel archaeal-specific ribosomal proteins. J. Mol. Biol. 405, 1215-1232 (2011).

Ruan, W., Lehmann, E., Thomm, M., Kostrewa, D., and Cramer, P.: Evolution of two modes of instrinsic RNA polymerase transcript cleavage. J. Biol.Chem. 286, 18701-18707 (2011).

Zeller, M.E. und Thomm, M.: Die RNA-Synthesemaschinerie von Archaeen: Ein Modell für die Molekularbiologie höherer Zellen. In: Blick in die Wissenschaft Nr. 24. Forschungsmagazin der Universität Regensburg, pp. 21-24 (2011).

Becker, T., Franckenberg, S., Wickles, S., Shoemaker, Ch.J., Anger, A.M., Armache, J.-P., Sieber, H., Ungewickell, Ch., Berninghausen, O., Daberkow, I., Karcher, A., Thomm, M., Hopfner, K.-P., Green, R., and Beckmann, R.: Structural basis of highly conserved ribosome recycling in eukaryotes and archaea. Nature, 482, 501-506 (2012). doi:10.1038/nature10829

Ochs, S., Thumann, S., Richau, R., Weiracuh, M.T., Lowe, T.M. Thomm, M., and Hausner W.: Activation of archaeal trascription mediated by recruitment of transcription factor. B.J. Biol. Chem. 587 (22), 18863-18871 (2012).

Publikationen zum Thema "Organismische Mikrobiologie":

Botz, R., Pokojski, H.-D., Schmitt, M. and Thomm, M.: carbon isotope fractionation during bacterial methanogenesis by CO2 reduction. Org. Geochem. 25, 255-262 (1996).

Jochimsen, B., Peinemann-Simon, S., Völker, H., Stüben, D., Botz, R., Stoffers, P. Dando, P. R. and Thomm, M.: Stetteria hydrogenophila, gen. nov. and sp. nov., a novel mixotrophic sulphur-dependent Crenarchaeote isolated from Milos/Greece. Extremophiles 1, 67-73 (1997).

Dando, P.R., Thomm, M., Arab, H., Brehmer, M., Hooper, L.E., Jochimsen, B., Schlesner, H., Stöhr, R., Miquel, J.-C., Fowler, S.W. Microbiology of shallow hydrothermal sites off Palaeochory Bay, Milos (Hellenic Volcanic Arc). Cah. Biol. Mar. 39, 369-372 (1998).

Dando, P. R., Aliani, S., Arab, H., Bianchi, C. N., Brehmer, M., Cocito, S., Fowler, S. W., Gundersen, J., Hooper, L. E., Kölbl, R., Küver, J., Linke, P., Makropoulos, K. C., Meloni, R., Miqueo, J.-C., Morri, C., Müller, S., Robinson, C., Schlesner, H., Sievert, S., Stöhr, R., Stüben, D., Thomm, M., Varnavas, S. P., and Ziebis, W. Hydrothermal studies in the Aegean Sea. Phys. Chem. Earth (B), 25 (1), 1-8 (2000).

Rothe, O., and Thomm, M. A simplified method for the cultivation of extreme anaerobic Archaea based on the use of sodium sulfite as reducing agent. Extremophiles 4, 247-252 (2000).

Arab, H., Völker, H., Thomm, M.: Thermococcus aegaeicus sp. nov. and Staphylothermus hellenicus sp. nov., two novel hyperthermophilic archaea isolated from geothermally heated vents off Palaeochori Bay, Milos, Greece. Int. J. Syst. Evol. Microbiol. 50, 2101-2108 (2000).

Schlesner, H., Lawson, P.A., Collins, M.D., Weiss, N., Wehmeyer, U., Völker, H., Thomm, M.: Filobacillus milensis gen. nov., sp. nov., a new halophilic spore-forming bacterium with Orn-D-Glu-type peptidoglycan. Int. J. Syst. Evol. Microbiol. 51, 425-431 (2001).

Stöhr, R., Waberski, A., Liesack, W., Völker, H., Wehmeyer, U., Thomm, M: Hydrogenophilus hirschii sp. nov., a new thermophilic hydrogen-oxidizing (ß-proteobacterium isolated from Yellowstone National Park. Int. J. Syst. Evol. Microbiol. 51, 481-488 (2001).

Stöhr, R., Waberski, A., Völker, H., Tindal, B.J., and Thomm, M.: Hydrogenothermus marinus gen. nov., sp. nov., a novel thermophilic hydrogen-oxidizing bacterium, recognition of Calderobacterium hydrogenophilum as a member of the genus Hydrogenobacter and proposal of the reclassification of Hydrogenobacter acidophilus as Hydrogenobaculum acidophilum, gen. nov., comb. nov., in the Hydrogenobacter/Aquifex phylum. Int. J. Syst. Evol. Microbiol. 51, 1853-1862 (2001).

von Klein, D., Arab, H., Völker, H., Thomm, M.: Methanosarcina baltica, spec. nov., a novel methanogen isolated from the Gotland Deep of the Baltic Sea. Extremophiles 6, 103-110 (2002).

Gade, D., Schlesner, H., Glöckner, F.O., Amann, R., Pfeiffer, S. and Thomm, M.: Identification of Planctomycetes with Order-, Genus-, and Strain-Specific 16S rRNA-Targeted Probes. Microbial Ecology 47, 243-251 (2004).

Etzel, K., Huber, H., Rachel, R., Schmalz, G., Thomm, M., and Depmeier, W.: Pyrite surface alteration of synthetic single crystals as effect of microbial activity and crystallographic orientation. Advanced Materials Research, 20-21, 350-353 (2007).

Pisa, K.Y., Huber, H., Thomm, M., and Müller, V.: A sodium ion-dependent A1A0 ATP synthase from the hyperthermophilic archaeon Pyrococcus furiosus. FEBS J., 274, 3928-3938 (2007).

Etzel, K., Klingl A. Huber, H., Rachel, R., Schmalz, G., Thomm, M., Depmeier, W.: Etching of {111} and {210} synthetic pyrite surfaces by two archaeal strains, Metallosphaera sedula and Sulfolobus metallicus. Hydrometallurgy, corrected proof, (2008).

Thomm, M.: Extremophile Archaea als Zeugen der Urzeit und Vorläufer der eukaryotischen Zelle. In: Evolution 150 Jahre nach Darwin. W. Gebhardt (ed.). Universitätsverlag Regensburg, pp. 69 -81 (2008).

Endreß, J., Thomm, M., and Hader, T.: In der Hitze Geboren. In: Pharma+Food – Effizienz im Hygieneprozess. A. Scheuermann (ed.). Hüthig Verlag, pp. 60-61 (2008).

Handayani, S., Santoso, I., Freisleben, H.-J., Huber, H., Andi, Ardiansyah, F., Mulyanto, C., Luthfa, Z., Saleh, R., Freisleben, S.K.U., Wanandi, S.I., and Thomm, M.: Archaeal life on tangkuban perahu-sampling and culture growth in Indonesian laboratories. HAYATI J.  Biosci., 19(3), 150-154 (2012).


Veröffentlichungen Prof. R. Wirth:

Wirth, R., Muscholl, A., Wanner, G.: The role of pheromones in bacterial interactions. Trends Microbiol. 4:96-103 (1996)

Marcinek, H., Wirth, R., Muscholl, A., Gauer, M.: Enterococcus faecalis gene transfer under natural conditions in municipal sewage water treatment plants. Appl. Env. Microbiol. 64:626-632 (1998)

Baumann, C., Judex, M., Huber, H., Wirth, R.: Estimation of genome sizes of hyperthermophiles. Extremophiles 2:101-108 (1998)

Muscholl-Silberhorn, A.: Analysis of the clumping-mediating domain(s) of sex pheromone plasmid pAD1-encoded aggregation substance. Eur. J. Biochem. 258:515-520 (1998)

Witte, W., Wirth, R., Klare, I: Enterococci. Chemotherapy 45:135-145 (1999)

Muscholl-Silberhorn, A.: Cloning and functional analysis of Asa373, a novel adhesin unrelated to the other sex pheromone plasmid-encoded aggregation substances of Enterococcus faecalis. Mol. Microbiol. 34:620-630 (1999)

Wirth, R.: Sex pheromones and gene transfer in Enterococcus faecalis. Res. Microbiol. 151:493-496 (2000)

Muscholl-Silberhorn, M.: Pheromone-regulated expression of sex pheromone plasmid pAD1-encoded aggregation substance depends on at least 6 upstream genes and a cis-acting, orientation dependent factor. J. Bacteriol. 182:3816-3825 (2000)

Süßmuth, S., Muscholl, A., Wirth, R., Susa, M., Marre, R., Rozdzinski, E.: Aggregation Substance Promotes Adherence, Phagocytosis, and Intracellular Survival of Enterococcus faecalis within Human Macrophages and Suppresses Respiratory Burst. Infect. Immun. 68:4900-4906 (2000)

Sartingen, S., Rozdzinski, E., Muscholl-Silberhorn, A., Marre, R.: Aggregation Substance Increases Adherence and Internalization, but Not Translocation, of Enterococcus faecalis through Different Intestinal Epithelial Cells In Vitro. Infect. Immun. 68:6044-6047 (2000)

Franz, C.M.A.P., Muscholl-Silberhorn, A.B., Yousif, N.M.K., Vancanneyt, M., Swings, J., Holzapfel, W.H.: Incidence of Virulence Factors and Antibiotic Resistance among Enterococci Isolated from Food. Appl. Environment. Microbiol. 67:4385-4389 (2001)

Waar, K., Muscholl-Silberhorn, A.B., Willems, R.J.L., Slooff, M.J.H., Harmsen, H.J.M., Degener, J.E.: Genogrouping and Incidence of Virulence Factors of Enterococcus faecalis in Liver Transplant Patients Differ from Blood Culture and Fecal Isolates. J. Infect. Dis. 185:1121-1127 (2002)

Schopf, S., G. Wanner, R. Rachel, and R. Wirth. An archaeal bi- species biofilm formed by Pyrococcus furiosus and Methanopyrus kandleri. Arch. Microbiol. DOI 10.1007/s00203-008-0371-9 (2008)

Thoma, C., M. Frank, R. Rachel, S. Schmid, D. Näther, G. Wanner, and R. Wirth. Fimbriae of Methanothermobacter thermoautotrophicus are encoded by mth60: first characterization of an archaeal fimbrium. Env. Microbiol. accepted. (2008)

Junglas, B., A. Briegel, T. Burghardt, P. Walther, R. Wirth, H. Huber, and R. Rachel. Ignicoccus hospitalis and Nanoarchaeum equitans: Ultrastructure, cell-cell interaction, and 3D reconstruction from serial sections of freeze-substituted cells and by electron cryotomography. Arch. Microbiol. DOI 10.1007/s00203-008-0402-6 (2008)

Burghardt, T., M. Saller, S. Gürster, D. Müller, C. Meyer, U. Jahn, R. Deutzmann, P. Babinger, R. Wirth, H. Huber, and R. Rachel. Insight into the proteome of the hyperthermophilic Crenarchaeon Ignicoccus hospitalis: the major cytosolic and membrane proteins. Arch. Microbiol. DOI 10.1007/s00203-008-0399-x (2008)


Veröffentlichungen Prof. Dr. R. Rachel:

W. Baumeister, B. Emde, B. Flaskamp, M. Hahn, R. Rachel, and W.O. Saxton (1981): Fine Structure of a Bacterial Cell Envelope Protein: The RS-Layer of Sporosarcina urea. Naturwissenschaften 67: 626-627

W. Baumeister, F. Karrenberg, R. Rachel, A. Engel, B. ten Heggeler, and W.O. Saxton (1982): The Major Cell Envelope Protein of Micrococcus radiodurans (R1): Structural and Chemical Characterization. Eur. J. Biochem. 125: 535-544

R. Rachel, A. Engel, and W. Baumeister (1983): Proteolysis of the major cell envelope protein of Deinococcus radiodurans remains morphologically latent. FEMS Microbiol. Lett. 17: 115-119

R. Rachel, U. Jakubowski, and W. Baumeister (1986): Electron Microscopy of Unstained, Freeze-Dried Macromolecular Assemblies. J. Microscopy 141: 179-191

R. Rachel, U. Jakubowski, H. Tietz, R. Hegerl, and W. Baumeister (1986): Projected structure of the surface protein of Deinococcus radiodurans determined to 8 Å resolution by cryomicroscopy. Ultramicroscopy 20: 305-316

R. Rachel (1987): Neuartige Präparationsmethoden für die Kryoelektronenmikroskopie biologischer Makromoleküle. Dissertation, Technische Universität München

R. Rachel, A.M. Engel, R. Huber, K.O. Stetter, and W. Baumeister (1990): A porin-type protein is the main constituent of the cell envelope of the ancestral eubacterium Thermotoga maritima. FEBS Letters 262: 64-68

U. Pley, J. Schipka, A. Gambacorta, H.W. Jannasch, H. Fricke, R. Rachel and K.O. Stetter (1991): Pyrodictium abyssi sp. nov. represents a novel heterotrophic marine archaeal hyperthermophile growing at 110°C. System. Appl. Microbiol. 14: 245 - 253

E. Drobner, H. Huber, R. Rachel, and K.O. Stetter (1992): Thiobacillus plumbophilus spec. nov., a novel galena and hydrogen oxidizer. Archives of Microbiology 157: 213 - 217

A.E. Dray, R. Rachel, W.O. Saxton, J. Lewis, M.S. Khan, A.M. Donald, and R.H. Friend (1992): Structure of a transition metal-containing poly-yne. Macromolecules 25: 3473 - 3479

A.E. Dray, R. Rachel, W.O. Saxton, A.M. Donald, R.H. Friend, M.S. Khan, and J. Lewis (1992): Beam damage in a transition metal-containing poly-yne. Ultramicroscopy 41: 83-88

R. Huber, T. Wilharm, D. Huber, A. Trincone, S. Burggraf, H. König, R. Rachel, I. Rockinger, H. Fricke, and K.O. Stetter (1992): Aquifex pyrophilus gen. nov. spec. nov., represents a novel group of marine hyperthermophilic hydrogen-oxidizing bacteria. System. Appl. Microbiol. 15: 340-351

P. Völkl, R. Huber, E. Drobner, R. Rachel, S. Burggraf, A. Trincone, K.O. Stetter (1993): Pyrobaculum aerophilum sp. nov., a novel nitrate-reducing hyperthermophilic Archaeum. Appl. Env. Microbiol. 59: 2918-2926

M. Schmidt, K. Rutkat, R. Rachel, G. Pfeifer, R. Jaenicke, P. Viitanen, G. Lorimer, and J. Buchner (1994): Symmetric Complexes of GroE Chaperonins as Part of the Functional Cycle. Science 265: 656-659

C. Cappellaro, C. Baldermann, R. Rachel, and W. Tanner (1994): Mating type-specific cell-cell recognition of Saccharomyces cerevisiae: cell wall attachment and active sites of a- and ?-agglutinin. EMBO J. 13: 4737-4744

H. Schurig, K. Rutkat, R. Rachel, and R. Jaenicke (1995): Octameric enolase from the hyperthermophilic bacterium Thermotoga maritima: Purification, characterization, and image processing. Protein Science 4: 228-236

G. Rieger, R. Rachel, R. Hermann, and K.O. Stetter (1995): Ultrastructure of the hyperthermophilic archaeon Pyrodictium abyssi. J. Struct. Biol. 115: 78-87

W. Behammer, Z. Shao, W. Mages, R. Rachel, K.O. Stetter, and R. Schmitt (1995): Flagellar structure and Hyperthermophily: Analysis of a single flagellin gene and its product in Aquifex pyrophilus. J. Bacteriol. 177: 6630-6637

R. Huber, J. Stöhr, S. Hohenhaus, R. Rachel, S. Burggraf, H.W. Jannasch, and K.O. Stetter (1995): Thermococcus chitonophagus sp. nov., a novel, chitin-degrading hyperthermophilic archaeum from a deep-sea hydrothermal vent environment. Arch. Microbiol. 164: 255-264

M. Keller, F.-J. Braun, R. Dirmeier, D. Hafenbradl, S. Burggraf, R. Rachel, and K.O. Stetter (1995): Thermococcus alcaliphilus, sp.nov., a new hyperthermophilic archaeum growing on polysulfide at alkaline pH. Archives Microbiology 164: 390-395

R. Huber, P. Roßnagel, C.R. Woese, R. Rachel, T.A. Langworthy, and K.O. Stetter (1996): Formation of ammonium from nitrate during chemolithoautotrophic growth of the extremely thermophilic bacterium Ammonifex degensii gen. nov. sp. nov. System. Appl. Microbiol. 19: 40-49

D. Hafenbradl, M. Keller, R. Dirmeier, R. Rachel, P. Roßnagel, S. Burggraf, H. Huber, and K.O. Stetter (1996): Ferroglobus placidus gen. nov., sp. nov., a novel hyperthermophilic archaeum that oxidizes Fe2+ at neutral pH under anoxic conditions. Arch. Microbiol. 166: 308-314

E. Blöchl, R. Rachel, S. Burggraf, D. Hafenbradl, H.W. Jannasch, and K.O. Stetter (1997): Pyrolobus fumarii, gen. and sp.nov. represents a novel group of archaea, extending the upper temperature limit for life to 113°C. Extremophiles 1: 14-21

H. Huber, H. Jannasch, R. Rachel, T. Fuchs, and K.O. Stetter (1997): Archaeoglobus veneficus sp. nov., a novel facultative chemolithoautotrophic hyperthermophilic sulfite reducer, isolated from abyssal black smokers. Syst. Appl. Microbiol. 20: 374-380

G. Rieger, K. Müller, R. Hermann, K.O. Stetter, and R. Rachel (1997): Cultivation of hyperthermophilic archaea in cellulose capillary tubes resulting in improved preservation of fine structure. Arch. Microbiol. 168: 373-379

N. Kröger, G. Lehmann, R. Rachel, and M. Sumper (1997): Characterization of a 200-kDa diatom protein that is specifically associated with a silica-based substructure of the cell wall. Eur. J. Biochem. 250: 99-105

R. Huber, D. Dyba, H. Huber, S. Burggraf, and R. Rachel (1998): Sulfur-inhibited Thermosphaera aggregans sp. nov., a new genus of hyperthermophilic archaea isolated after its prediction from environmentally derived 16S rRNA sequences. Int. J. Syst. Bacteriol. 48: 31-38

R. Grimm, H. Singh, R. Rachel, D. Typke, W. Zillig, and W. Baumeister (1998): Electron tomography of ice-embedded prokaryotic cells. Biophys. J. 74: 1031-1042

R. Dirmeier, M. Keller, D. Hafenbradl, F.-J. Braun, R. Rachel, S. Burggraf, and K.O. Stetter (1998): Thermococcus acidaminovorans sp. nov., a new hyperthermophilic alcalophilic archaeon growing on amino acids. Extremophiles 2: 109-114

R. Huber, W. Eder, S. Heldwein, G. Wanner, H. Huber, R. Rachel, and K.O. Stetter (1998): Thermocrinis ruber gen. nov., sp. nov., a pink-filament-forming hyperthermophilic bacterium isolated from Yellowstone National Park. Appl. Env. Microbiol. 64: 3576-3583

T. Minuth, G. Frey, P. Lindner, R. Rachel, K.O. Stetter, and R. Jaenicke (1998): Recombinant homo- and hetero-oligomers of an ultrastable chaperonin from the archaeon Pyrodictium occultum show chaperone activity in vitro. Eur. J. Biochem. 258: 837-845

T. Minuth, M. Henn, K. Rutkat, S. Andrä, G. Frey, R. Rachel, K.O. Stetter, and R. Jaenicke (1999): The rekombinant thermosome from the hyperthermophilic archaeon Methanopyrus kandleri: in vitro analysis of its chaperone activity . Biol. Chem. 380: 55-62

B. Schuler, R. Rachel, and R. Seckler (1999): Formation of fibrous aggregates from a non-native intermediate: the isolated p22 tailspike ?-helix domain. J. Biol. Chem. 274: 18589-18596

H. Huber, S. Burggraf, T. Mayer, I. Wyschkony, R. Rachel, and K.O. Stetter (2000): Ignicoccus gen. nov., a novel genus of hyperthermophilic, chemolithoautotrophic archaea, represented by two new species, Ignicoccus islandicus sp.nov. and Ignicoccus pacificus sp. nov. Int. J. Syst. Evol. Microbiol. 50: 2093-2100

R. Deutzmann, S. Fowler, X. Zhang, K. Boone, S. Dexter, R.P. Boot-Handford, R. Rachel, and M.P. Sarras (2000): Molecular, biochemical and functional analysis of a novel and developmentally important fibrillar collagen (Hcol-I) in hydra. Development-Cambridge 127: 4669-4680

B. Scharf, H. Schuster-Wolff-Bühring, R. Rachel, and R. Schmitt (2001): Mutational analysis of the Rhizobium lupini H13-3 and Sinorhizobium meliloti flagellin genes: Importance of flagellin A for flagellar filament structure and transcriptional regulation. J. Bacteriol. 183: 5334-5342

R. Rachel, I. Wyschkony, S. Riehl, and H. Huber (2002): The ultrastructure of Ignicoccus: Evidence for a novel outer membrane and for intracellular vesicle budding in an archaeon. Archaea 1: 9-18

H. Huber, M.J. Hohn, R. Rachel, T. Fuchs, V.C. Wimmer, and K.O. Stetter (2002): A new phylum of Archaea represented by a nanosized hyperthermophilic symbiont. Nature 417: 63-67

H. Huber, S. Diller, Ch. Horn, and R. Rachel (2002): Thermovibrio ruber gen.nov., sp.nov., an extremely thermophilic, chemolithoautotrophic, nitrate-reducing bacterium that forms a deep branch within the phylum Aquificae. Int. J. Syst. Evol. Microbiol. 52: 1-7

R. Rachel, M. Bettstetter, B.P. Hedlund, M. Häring, A. Kessler, K.O. Stetter, and D. Prangishvili (2002): Remarkable morphological diversity of viruses and virus-like particles in hot terrestrial environments. Arch. Virology 147: 2419-2429 (doi 10.1007/s00705-002-0895-2)

S. Nickell, R. Hegerl, W. Baumeister, and R. Rachel (2003): Pyrodictium cannulae enter the periplasmic space but do not enter the cytoplasm, as revealed by cryo-electron tomography. J. Struct. Biol. 141(1): 34-42 (doi 10.1016/S1047-8477(02)00581-6)

C. Moissl, C. Rudolph, R. Rachel, M. Koch, and R. Huber (2003): In situ growth of the novel SM1 euryarchaeon from the string-of-pearls-like microbial community in its cold biotope, its physical separation and insights into its structure and physiology. Arch. Microbiol. 180: 211-217

D.J. Näther and R. Rachel (2004): The outer membrane of the hyperthermophilic archaeon Ignicoccus: dynamics, ultrastructure and composition. Biochem. Soc. Transact. 32: 199-203

I. Hagen, M. Ecker, A. Lagorce, J.M. Francois, S. Sestak, R. Rachel, G. Grossmann, N.C. Hauser, J.D. Hoheisel, W. Tanner and S. Strahl (2004): Sed1p and Srl1p are required to compensate for cell wall instability in Saccharomyces cerevisiae mutants defective in multiple GPI-anchored mannoproteins. Mol. Microbiol. 52: 1413-1425

M. Häring, X. Peng, K. Brügger, R. Rachel, K.O. Stetter, R.A. Garrett, and D. Prangishvili (2004): Morphology and genome organisation of the virus PSV of the hyperthermophilic archaeal genera Pyrobaculum and Thermoproteus: a novel virus family, the Globuloviridae. Virology 323: 233-242

T. Urich, T.M. Bandeiras, S.S. Leal, R. Rachel, T. Albrecht, P. Zimmermann, C. Scholz, M. Teixeira, C.M. Gomes, and A. Kletzin (2004): The sulphur oxygenase reductase from Acidianus ambivalens is a multimeric protein containing a low-potential mononuclear non-haem iron centre. Biochemical J. 380: 1-10

R. Rachel (2004): Heiße Mikroorganismen und 'coole' Präparationsmethoden: Ultrastruktur, Oberflächen, Volumina und Interaktionen hyperthermophiler Bakterien und Archaeen. Habilitationsschrift. Naturwissenschaftliche Fakultät III für Biologie und vorklinische Medizin, Universität Regensburg.

Ch. Moissl, R. Rachel, A. Briegel, H. Engelhardt, and R. Huber (2005): The unique structure of archaeal 'hami', highly complex cell appendages with nano-grappling hooks. Mol. Microbiol. 56: 361-370 (doi: 10.1111/j.1365-2958.2005.04294.x)

M. Häring, G. Vestergaard, K. Brügger, R. Rachel, R.A. Garrett and D. Prangishvili (2005): Structure and genome organisation of AFV2, a novel filamentous archaeal virus with unusual terminal structures. J. Bacteriol. 187(11), 3855-3858

G. Vestergaard, M. Häring, X. Peng, R. Rachel, R.A. Garrett and D. Prangishvili (2005): A novel rudivirus, ARV1, of the hyperthermophilic archaeal genus Acidianus. Virology 336, 83-92

G.J. Schneider, S.A. Fink, R. Rachel and D. Göritz (2005): Three-dimensional structure of precipitated silica as determined by electron tomography. KGK Kautschuk Gummi Kunststoffe 58: 461-463

M. Häring, R. Rachel, X. Peng, R.A. Garrett and D. Prangishvili (2005): Viral diversity in hot springs of Pozzuoli, Italy, and characterization of a unique archaeal virus, Acidianus bottle-shaped virus, from a new familiy, the Ampullaviridae. J. Virology 79 (15): 9904-9911

M. Häring, G. Vestergaard, R. Rachel, L. Chen, R.A. Garrett and D. Prangishvili (2005): Independent virus development outside a host. Nature 436: 1101-1102.

C. Blumer, A. Kleefeld, D. Lehnen, M. Heintz, U. Dobrindt, G. Nagy, K. Michaelis, L. Emödy, T. Polen, R. Rachel, V.F. Wendische and Gottfried Unden (2005): Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli. Microbiology 151: 3287-3298

V.N. Krylov, S. Miller, R. Rachel, M. Biebl, E.A. Pleteneva, M. Schuetz, S.V. Krylov, and O.V. Shaburova (2006): Ambivalent bacteriophages of different species active on Escherichia coli and Salmonella sp. strains. Russian J. of Genetics 42: 106-114

E. Eggenhofer, R. Rachel, M. Haslbeck, and B. Scharf (2006): MotD of Sinorhizobium meliloti and related ?-proteobacteria is the flagellar hook-length regulator and therefore re-assigned as FliK. J. Bacteriol. 188: 2144-2153

D. Prangishvili, G. Vestergaard, M. Häring, R. Aramayo, T. Basta, R. Rachel, R.A. Garrett (2006): Structural and genomic properties of the hyperthermophilic archaeal virus ATV with an extracellular stage of the reproductive cycle. J. Mol. Biol. 359: 1203-1216

D.J. Näther, R. Rachel, G. Wanner, and R. Wirth (2006): Flagella of Pyrococcus furiosus are multifunctional organelles, also serving for surface adhesion and cell-cell contacts. J. Bacteriol. 188: 6915-6923

T. Burghardt, D.J. Näther, B. Junglas, H. Huber and R. Rachel (2007): The dominating outer membrane protein of the hyperthermopilic Archaeum Ignicoccus hospitalis: a novel pore-forming complex. Mol. Microbiol. 63: 166-176 (doi: 10.1111/j.1365-2958.2006.05509.x)

W. Paper, U. Jahn, M.J. Hohn, M. Brandl, D.J. Näther, T. Burghardt, R. Rachel, K.O. Stetter and H. Huber (2007): Ignicoccus hospitalis sp. nov., the host of Nanoarchaeum equitans. Int J Syst Evol Microbiol 57: 803-808 (DOI 10.1099/ijs.0.64721-0)

H. Suleiman, D. Heudobler, A.-S. Raschta, Y. Zhao, Q. Zhao, I. Hertting, H. Vitzthum, M.J. Moeller, L.B. Holzman, R. Rachel, R. Johnson, H. Westphal, A. Rascle, Ralph Witzgall (2007): The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes. Developmental Biology 304: 701-712 (doi:10.1016/j.ydbio.2007.01.020)

K. Etzel, H. Huber, R. Rachel, G. Schmalz, M. Thomm, and W. Depmeier (2007): Pyrite surface alteration of synthetic single crystals as effect of microbial activity and crystallographic orientation. Advanced Materials Research Vols. 20-21, 350-353

G. Vestergaard, R. Aramayo, T. Basta, M. Häring, X. Peng, K. Brügger, L. Chen, R. Rachel, N. Boisset, R.A. Garrett and D. Prangishvili (2008): Structure of the Lipothrixvirus AFV3 and comparative genomics of related viruses from the hyperthermophilic archaeal genus Acidianus J. Virology 82: 371-381 (DOI:10.1128/JVI.01410-07)

S. Dröge, R. Rachel, R. Radek and H. König (2008): Treponema isoptericolens sp. nov., a novel spirochaete from the hindgut of the termite Incisitermes tabogae. Int J Syst Evol Microbiol 58: 1079-1083 (DOI: 10.1099/ijs.0.64699-0)

M. Walter, C. Fiedler, R. Grassl, M. Biebl, R. Rachel, X.L. Hermo-Parrado, A.L. Llamas-Saiz, R. Seckler, S. Miller, M.J. van Raaij (2007): Structure of the receptor-binding protein of bacteriophage Det7: A podoviral tailspike in a myovirus. to be submitted to J. Virology

M. Walter, C. Fiedler, R. Grassl, M. Biebl, R. Rachel, X.L. Hermo-Parrado, A.L. Llamas-Saiz, R. Seckler, S. Miller, M.J. van Raaij (2008): Structure of the receptor-binding protein of bacteriophage Det7: A podoviral tailspike in a myovirus. J. Virology 82: 2265-2273 (DOI:10.1128/JVI.01641-07)

U. Jahn, M. Gallenberger, W. Paper, B. Junglas, W. Eisenreich, K.O. Stetter, R. Rachel and H. Huber (2008): Nanoarchaeum equitans and Ignicoccus hospitalis: new insights into a unique, intimate association of two Archaea. J. Bacteriol. 190: 1743-1750 (DOI:10.1128/JB.01731-07)

S. Schopf, G. Wanner, R. Rachel, R. Wirth (2008): An archaeal bi-species biofilm formed by Pyrococcus furiosus and Methanopyrus kandleri. Arch. Microbiol. 190, 371-377 (DOI = 10.1007/s00203 008 0371 9)

T. Burghardt, M. Saller, S. Gürster, D. Müller, C. Meyer, U. Jahn, E. Hochmuth, R. Deutzmann, F. Siedler, P. Babinger, R. Wirth, H. Huber and R. Rachel (2008): Insight into the proteome of the hyperthermophilic Crenarchaeon Ignicoccus hospitalis: the major cytosolic and membrane proteins. Arch. Microbiol. 190, 379-394 (DOI: 10.1007/s00203-008-0399-x)

B. Junglas, A. Briegel, T. Burghardt, P. Walther, H. Huber, R. Rachel (2008): Ignicoccus hospitalis and Nanoarchaeum equitans: Ultrastructure, cell-cell interaction, and 3D reconstruction from serial sections of freeze-substituted cells and by electron cryotomography. Arch. Microbiol. 190, 395-408 (DOI: 10.1007/s00203-008-0402-6)

C. Thoma, M. Frank, R. Rachel, S. Schmid, D. Näther, G. Wanner and R. Wirth (2008): The Mth60-fimbriae of Methanothermobacter thermoautotrophicus are functional adhesins. Environ. Microbiol. 10: 2785-2795 (DOI:10.1111/j.1462-2920.2008.01698.x)

G. Vestergaard, S.A. Shah, A. Bize, W. Reitberger, M. Reuter, H. Phan, A. Briegel, R. Rachel, R.A. Garrett and D. Prangishvili (2008): Stygiolobus rod-shaped virus and the Interplay of Crenarchaeal Rudiviruses with the CRISPR antiviral system. J. Bacteriol. 190: 6837-6845 (DOI:10.1128/JB.00795-08)

M.G. Pyatibratov, S.N. Beznosov, R. Rachel, E.I. Tiktopulo, A.K. Surin, A.S. Syutkin, O.V. Fedorov (2008): Alternative flagellar filament types in the haloarchaeon Haloarcula marismortui. Can. J. Microbiology 54: 835-844 (doi:10.1139/W08-076).

M. Podar, I. Anderson, K.S. Makarova, J. G. Elkins, N. Ivanova, M. Wall, A. Lykidis, K. Mavrommatis, H. Sun, M. Hudson, W. Chen, C. Deciu, D. Hutchison, J. R. Eads, A. Anderson, F. Fernandez, E. Szeto, A. Lapidus, N. Kyrpides, M. Saier, P. Richardson, R. Rachel, H. Huber, J.A. Eisen, E.V. Koonin, M. Keller and K.O. Stetter (2008). A genomic analysis of the archaeal system Ignicoccus hospitalis – Nanoarchaeum equitans. Genome Biology 2008, 9:R158 (doi:10.1186/gb-2008-9-11-r158)

T. Burghardt, B. Junglas, F. Siedler, R. Wirth, H. Huber, R. Rachel (2009). On the interaction of Nanoarchaeum equitans with Ignicoccus hospitalis: Proteins in the contact site between two cells. Biochem. Soc. Transactions 37, 127-132 (doi: 10.1042/BST0370127).

W. Minuth, L. Denk, C. Meese, R. Rachel, A. Roessger (2009). Ultrastructural insights in the interface between generated renal tubules and a polyester interstitium. Langmuir 25: 4621-4627 (DOI: 10.1021/la803858q).

K. Beblo, E. Rabbow, R. Rachel, H. Huber, P. Rettberg (2009). Tolerance of thermophilic and hyperthermophilic microorganisms to desiccation. Extremophiles 13: 521-531 (DOI 10.1007/s00792-009-0239-1).

A. ElBakry, A. Zaky, R. Liebl, R. Rachel, A. Göpferich, M. Breunig (2009). Layer-by-Layer assembled gold nanoparticles for siRNA delivery. Nano Letters 9(5), 2059-2064 (DOI: 10.1021/nl9003865).

A. Veith, A. Klingl, B. Zolghadr, K. Lauber, R. Mentele, F. Lottspeich, R. Rachel, S.-V. Albers, and A. Kletzin (2009). Acidianus, Sulfolobus and Metallosphaera Surface Layers: Structure, Composition and Gene Expression Molecular Microbiology 73: 58-72 (doi:10.1111/j.1365-2958.2009.06746.x).

V. Strádalová, W. Stahlschmidt, G. Grossmann, M. Blažiková, R. Rachel, W. Tanner, J. Malinsky (2009). Furrow-like invaginations of the yeast plasma membranes correspond to membrane compartment of Can1 J. Cell Science, in press (doi: 10.1242/jcs.051227).

D.W. Müller, C. Meyer, S. Gürster, U. Küper, H. Huber, R. Rachel, G. Wanner, R. Wirth, A. Bellack (2009). The Iho670 fibers of Ignicoccus hospitalis: a new type of archaeal cell surface appendage. J. Bacteriol., accepted for publication.

R. Rachel (2009). Another way to divide: the case of anammox bacteria. Mol. Microbiol., in press.


Veröffentlichungen Dr. H. Huber:

Parey K., Fielding A.J., Sörgel M., Rachel R., Huber H., Ziegler C., Rajendran C.: Crystal structure of a novel membrane-associated octaheme cytochrome c nitrite reductase from the Crenarchaeum Ignicoccus hospitalis. J. Biol. Chem. (2015) in press.


Pintoa A.F., Romãoa C.V., Pintoa L.C., Huber H., Saraivaa L.M., Todorovica S., Cabellic D., Teixeira M.: Superoxide reduction by a superoxide reductase lacking the highly conserved lysine residue. J. Biol. Inorg. Chem. 20:155-64 (2015) DOI: 10.1007/s00775-014-1222-6.


Malik A., Santoso I., Yehuda A., Freisleben S.K.U., Wanandi S.I., Huber H., Luthfa Z., Saleh R., Freisleben H.-J.: Characterization of Thermoplasma species cultured from sampling on Tangkuban Perahu,  Indonesia. Microbiol. Indones. 8:16-23 (2014).

Perras A.K., Wanner G., Klingl A., Mora M., Auerbach A.K., Heinz V., Probst A.J., Huber H., Rachel R., Meck S., Moissl-Eichinger C.: Grappling archaea: ultrastructural analyses of an uncultivated, cold-loving archaeon and its biofilm. Front. Microbiology (2014) doi: 10.3389/fmicb.2014.00397.

Naß B., Pöll U., Langer J., Kreuter L., Küper U., Flechsler J., Heimerl T., Rachel R., Huber H., Kletzin A.: Three multiheme cytochromes c from the hyperthermophilic Archaeon Ignicoccus hospitalis: purification, properties and localization. Microbiology 160:1278-1289 (2014).

Richard J. Giannone*, Louie L. Wurch*, Thomas Heimerl, Stanton Martin, Zamin Yang, Harald Huber, Reinhard Rachel, Robert L. Hettich, and Mircea Podar: Life on the edge: Functional genomic response of Ignicoccus hospitalis to the presence of Nanoarchaeum equitans. ISME Journal (2014) doi: 10.1038/ismej.2014.112.

Gagen E., Huber H., Meador T., Hinrichs K-U., Thomm M.: A novel cultivation-based approach for understanding the Miscellaneous Crenarchaeotic Group (MCG) Archaea from sedimentary ecosystems. Appl. Environ. Microbiol 79:6400-6406 (2013).

Huber H., Kreuter L.: Nanoarchaeota. Prokaryotes (2014)

Morris, B.E.L., Henneberger, R., Huber, H., Moissl-Eichinger, C.: Microbial syntrophy: interaction for the common good. FEMS Microbiol Rev 37:384–406 (2013).

Simona Lobasso, Patrizia Lopalco, Roberto Angelini, Rita Vitale, Harald Huber, Volker Mueller, Angela Corcelli: Coupled TLC and MALDI-TOF/MS analyses of the lipid extract of the hyperthermophilic archaeon Pyrococcus furiosus. Archaea [doi:10.1155/2012/957852] (2012).

Sri Handayani, Iman Santoso, Hans-Joachim Freisleben, Harald Huber, Andi, Fery Ardiansyah, Cenmi Mulyanto, Zessinda Luthfa, Rosari Saleh, Seruni K.U. Freisleben, Septelia Inawati Wanandi, Michael Thomm: Archaeal life on Tangkuban Perahu- sampling and culture growth in Indonesian laboratories. HAYATI J. Biosciences 19:150-154 (2012).

Huber, H., Küper, U., Meyer, C., Daxer, S., Rachel, R.: The unusual cell biology of the hyperthermophilic Crenarchaeon Ignicoccus hospitalis. Antonie v. Leeuwenhoek 102:203–219 (2012) [DOI 10.1007/s10482-012-9748-5].

Moissl-Eichinger, Ch., Huber, H.: Archaeelle Symbionten und Parasiten. BIOspektrum 18:100–107 (2012).

Mayer, F., Küper, U., Meyer, C., Daxer, S., Müller, V., Rachel, R., Huber, H.: An AMP-forming acetyl-CoA synthetase in the outermost membrane of the hyperthermophilic Cren­archaeon Ignicoccus hospitalis. J. Bact. 194:1572–1581 (2012) [doi: 10.1128/JB.06130-11].

Srinivasan, V., Morowitz, H.J., Huber H.: What is an Autotroph? Arch. Microbiol. 194:135-140 (2012) [doi: 10.1007/s00203-011-0755-0].

Binner, R., Menath, V., Huber, H., Thomm, M., Bischof, F., Schmack, D., Reuter, M.: Comparative study of stability and halflife of enzymes and enzyme aggregates implemented in anaerobic biogas processes. Biomass Conv. Bioref. (2011) 1:1-8 [DOI 10.1007/s13399-010-0002-y].

Pinho, F.G., Pinto, A.F., Pinto, L.C., Huber, H., Rom˜ao, C.V., Teixeira, M., Matias, P.M., Bandeiras, T.M.: Superoxide reductase from Nanoarchaeum equitans: expression, purifica­tion, crystallization and preliminary X-ray crystallographic analysis. Acta Crystallographica Section F 67:591-595 (2011) [doi: 10.1107/S1744309111009432].

Bellack, A., Huber, H., Rachel, R., Wanner, G., Wirth, R.: Methanocaldococcus villosus sp. nov., a heavily flagellated archaeon adhering to surfaces and forming cell-cell contacts. Int. J. Syst. Evol. Microbiol. 61:1239-1245 (2011) [doi: 10.1099/ijs.0.023663-0].

Anderson I, Göker M, Nolan M, Lucas S, Hammon N, Deshpande S, Cheng JF, Tapia R, Han C, Goodwin L, Pitluck S, Huntemann M, Liolios K, Ivanova N, Pagani I, Mavromatis K, Ovchinikova G, Pati A, Chen A, Palaniappan K, Land M, Hauser L, Brambilla EM, Huber H, Yasawong M, Rohde M, Spring S, Abt B, Sikorski J, Wirth R, Detter JC, Woyke T, Bristow J, Eisen JA, Markowitz V, Hugenholtz P, Kyrpides NC, Klenk HP, Lapidus A.: Complete genome sequence of the hyperthermophilic chemolithoautotroph Pyrolobus fumarii type strain (1AT). Standards in Genomic Sciences 4(3):381-392 (2011).

Estelmann, S., Ramos-Vera, W.H., Gad’on, N., Huber, H., Berg, I.A., Fuchs, G.: Carbon dioxide fixation in ‘Archaeoglobus lithotrophicus’: are there multiple autotrophic pathways? FEMS Microbiol. Lett. 319:65–72 (2011).

Giannone, R.J., Huber, H., Karpinets, T., Heimerl, T., Küper, U., Rachel, R., Keller, M., Hettich, R.L., Podar, M.: Proteomic Characterization of Cellular and Molecular Processes that Enable the Nanoarchaeum equitans-Ignicoccus hospitalis Relationship. PLoS ONE 6(8): e22942. (2011) [doi: 10.1371/journal.pone.0022942].

Klingl, A., Moissl-Eichinger, Ch., Wanner, G., Zweck, J., Huber, H., Thomm, M., Rachel, R.: Analysis of the surface proteins of Acidithiobacillus ferrooxidans strain SP5/1 and the new, pyrite-oxidizing Acidithiobacillus isolate HV2/2, and their possible involvement in pyrite oxidation. Arch. Microbiol. 193:867-882 (2011).

Moissl-Eichinger, Ch., Huber, H.: Archaeal symbionts and parasites. Current Opinion in Microbiology 14:1–7 (2011).

Huber, H., Rachel, R.: Die Feuerkugel und ihr Urzwerg: Rätselhafte Lebensgemeinschaft im Reich der Archaea. BIUZ 41:102-109 (2011).

Beblo, K., Douki T., Schmalz, G., Rachel, R., Wirth, R., Huber, H., Reitz, G., Rettberg, P.: Survivival of thermophilic and hyperthermophilic microorganisms after exposure to UV-C, ionizing radiation and desiccation. Arch. Microbiol. 193:797-809 (2011) [doi: 10.1007/S00203-011-0718-5].

Küper, U., Rachel, R., Meyer, C., Müller, V., Huber, H.: Ignicoccus hospitalis und sein Weg ATP zu gewinnen. Biospektrum, 16, 628-631 (2010).

Küper, U., Meyer, C., Müller, V., Rachel, R., Huber, H.: Energized outer membrane and spatial separation of metabolic processes in the hyperthermophilic Archaeon Ignicoccus hospitalis. PNAS 107, 3152-3156 (2010) [doi: 10.1073/pnas.091171107].

Pinho, F.G., Romao, C.V., Pinto, A.F., Saraiva, L.M., Huber, H., Matias, P.M., Teixeira, M.,  Bandeiras, T.M.: Cloning, purification, crystallization and X-ray crystallographic analysis of Ignicoccus hospitalis neelaredoxin. Acta Crystallographica Section F, 66, 605-607 (2010) [doi:10.1107/S1744309110012030].

Berg, I.A., Ramos-Vera, W.H., Petri, A., Huber, H., Fuchs, G.: Study of the distribution of autotrophic CO fixation cycles in Crenarchaeota, Microbiology, 156, 256-269 (2010); doi:10.1099/mic.0.034298-0.

Anderson, I.J., Dharmarajan, L., Rodriguez, J., Hooper, S., Porat, I., Ulrich, L.E., Elkins, J.G., Mavromatis, K., Sun, H., Land, M., Lapidus, A., Lucas, S., Barry, K., Huber, H., Zhulin, I.B., Whitman, W.B., Mukhopadhyay, B., Woese, C., Bristow, J., Kyrpides, N.: The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota. BMC Genomics, 10, 145-157 (2009) [doi:10.1186/1471-2164-10-145].

Beblo, K., Rabbow, E., Rachel, R., Huber, H., Rettberg, P.: Tolerance of thermophilic and hyperthermophilic microorganisms to desiccation. Extremophiles 13, 521-531 (2009).

Burghardt, T., Junglas, B., Siedler, F., Wirth, R., Huber, H., Rachel, R.: The interaction of Nanoarchaeum equitans with Ignicoccus hospitalis: proteins in the contact site between two cells. Biochem. Soc. Transactions, 37, 127-132 (2009).

Friedrich-Jahn, U., Aigner, J., Längst, G., Reeve, J. N., Huber, H.: Nanoarchaeal origin of histone H3? J. Bact. 191, 1092-1096 (2009).

Podar M., Anderson I., Makarova K.S., Elkins J.G., Ivanova N., Wall M., Lykidis A., Mavrommatis K., Sun H., Chen W., Deciu C., Hutchison D., Eads J.R., Anderson A., Fernandes F., Szeto E., Lapidus A., Kyrpides N., Saier M.H., Richardson P., Rachel R., Huber H., Eisen J.A., Koonin E.V., Keller M., Stetter K.O.: A genomic analysis of the archaeal system Ignicoccus hospitalis - Nanoarchaeum equitans. Genome Biology 9 (11), R158 (2008).

Lundgren, M., Malandrin, L., Eriksson, S., Huber, H., Bernander, R.: Cell cycle characteristics of Crenarchaeota: Unity among diversity. J. Bact. 190, 5362-5367 (2008).

Burghardt, T., Saller, M., Gürster, S., Müller, D., Meyer, C., Jahn, U., Hochmuth, E., Deutzmann, R., Siedler, F., Babinger P., Wirth, R., Huber, H., Rachel, R.: Insight into the proteome of the hyperthermophilic Crenarchaeon Ignicoccus hospitalis: the major cytosolic and membrane proteins. Arch. Microbiol. 190, 379-394 (2008).

Huber, H. and Soppa, J.: Gene regulation and genome function in Archaea: a progress survey. Arch. Microbiol. 190, 195-196 (2008).

Huber, H., Gallenberger, M., Jahn, U., Eylert, E., Berg, I., Kockelkorn, D., Eisenreich, W., Fuchs, G.: A dicarboxylate/4-hydroxybutyrate autotrophic carbon assimilation cycle in the hyperthermophilic Archaeum Ignicoccus hospitalis. PNAS 105, 7851-7856 (2008).

Etzel, K., Klingl A. Huber, H., Rachel, R., Schmalz, G., Thomm, M., Depmeier, W.: Etching of {111} and {210} synthetic pyrite surfaces by two archaeal strains, Metallosphaera sedula and Sulfolobus metallicus. Hydrometallurgy, 94:116-120 (2008).

Jahn, U., Gallenberger, M., Paper, W., Junglas, B., Stetter, K. O., Eisenreich, W., Rachel, R. and Huber H.: Nanoarchaeum equitans and Ignicoccus hospitalis: new insights into a unique, intimate association of two Archaea. J. Bact. 190, 1743-1750 (2008).

Rodrigues J.V., Victor B.L., Huber H., Saraiva L.M., Soares C.M., Cabelli D.E., Teixeira M.: Superoxide reduction by Nanoarchaeum equitans neelaredoxin, an enzyme lacking the highly conserved glutamate iron ligand. J. Biol. Inorg. Chem. 13, 219-228 (2008).

Kelly D.P., Uchino Y., Huber H., Amils R., Wood A.P.: Reassessment of the phylogenetic relationships of Thiomonas cuprina. Int. J. Syst. Evol. Microbiol. 57, 2720-2724 (2007).

Hügler M., Huber H., Molyneaux S.J., Vetriani C., Sievert S. M.: Autotrophic CO fixation via the reductive tricarboxylic acid cycle in different lineages within the phylum Aquificae: Evidence for two ways of citrate cleavage. Environ. Microbiol. 9, 81-92 (2007).

Burghardt T., Näther D.J., Junglas B., Huber H., Rachel R.: The dominating outer membrane protein of the hyperthermophilic Archaeum Ignicoccus hospitalis: a novel pore-forming complex. Molec. Microbiol. 63, 168-176 (2007).

Paper W., Jahn U., Hohn M.J., Kronner M., Näther D.J., Burghardt T., Rachel R., Stetter K.O., Huber H.: Ignicoccus hospitalis sp. nov., the host of “Nanoarchaeum equitans”. Int. J. System. Evol. Microbiol. 57, 803-808 (2007).

Etzel, K., Huber, H., Rachel, R., Schmalz, G., Thomm, M., Depmeier, W.: Pyrite surface alteration of synthetic single crystals as effect of microbial activity and crystallographic orientation. Adv. Mat. Res. 20-21, 350-353 (2007).

Pisa K.Y., Huber, H., Thomm M., Müller, V.: A sodium ion-dependent A1A0 ATP synthase from the hyperthermophilic archaeon Pyrococcus furiosus. FEBS J. 274:3928-3938 (2007).

Jahn, U., Huber, H., Eisenreich, W., Hügler, M., Fuchs, G.: Insights into the autotrophic CO fixation pathway of the archaeon Ignicoccus hospitalis: comprehensive analysis of the central carbon metabolism. J. Bacteriol. 189, 4108-4119 (2007).

Huber, H., Crimmann, P., Bendix, D., Roth, K.: Neuentwicklung eines Korrosionstestsystems: Hochtemperaturmikroben als Prüfingenieure. In: Verfahren & Werkstoffe für die Energietechnik, Band 2: Korrosion in Anlagen zur regenerativen Energieerzeugung, (M. Faulstich und D. Bendix eds.). Förster Verlag, Sulzbach-Rosenberg, Germany, pp. 97-110 (2006)

Huber, H.: Crenarchaeota. In: ENCYCLOPEDIA OF LIFE SCIENCES. John Wiley & Sons, Ltd: Chichester http://www.els.net/ [doi: 10.1038/npg.els.0004242] (April 2006).

Huber, H.: Euryarchaeota. In: ENCYCLOPEDIA OF LIFE SCIENCES. John Wiley & Sons, Ltd: Chichester http://www.els.net/ [doi: 10.1038/npg.els.0004243] (April 2006).

Huber, H., Prangishvili, D.: “Sulfolobales” In: M. Dworkin et al., eds., The Prokaryotes: An evolving electronic resource for the microbiological community, 3rd edition, release 3.17, 22th August 2004, Springer-Verlag, New York, www.prokaryotes.com.

Jahn, U., Summons, R., Sturt, H., Grosjean, E., Huber, H.: Composition of the lipids Nanoarchaeum equitans and their origin from its host Ignicoccus sp. strain KIN4/I. Arch. Microbiol. 182, 404-413 (2004).

Hügler M., Huber, H., Stetter, K.O., Fuchs, G.: Autotrophic CO fixation pathways in archaea (Crenarchaeota). Arch. Microbiol. 179, 160-173 (2003).

Huber, H., Hohn, M.J., Jahn, U., Rachel, R.: Heiß, klein und „gemein”: das neue Phylum der “Nanoarchaeota“. Biospektrum 9, 353-355 (2003).

Huber, H., Hohn, M.J., Rachel, R., Stetter, K.O.: “Nanoarchaeota” in M. Dworkin et al., eds., The Prokaryotes: An evolving electronic resource for the microbiological community, 3rd edition, release 3.15, 22th March 2003, Springer-Verlag, New York, www.prokaryotes.com.

Huber, H., Hohn, M.J., Stetter, K.O., Rachel, R.: The phylum Nanoarchaeota: Present knowledge and future perspectives of a unique form of life. Res. Microbiol. 154, 165-171 (2003).

Hohn, M.J., Hedlund, B.P., Huber, H.: Detection of 16S rDNA sequences representing the novel phylum „Nanoarchaeota”: indication for a wide distribution in high temperature biotopes. System. Appl. Microbiol. 25, 551-554 (2002).

Huber, H., Stetter, K.O.: “Desulfurococcales,” in M. Dworkin et al., eds., The Prokaryotes: An evolving electronic resource for the microbiological community, 3rd edition, release 3.11, 22th November 2002, Springer-Verlag, New York, www.prokaryotes.com.

Huber, H., Huber, R., Stetter, K.O.: “Thermoproteales,” in M. Dworkin et al., eds., The Prokaryotes: An evolving electronic resource for the microbiological community, 3rd edition release 3.10, 26th September 2002, Springer-Verlag, New York, www.prokaryotes.com.

Huber, H., Diller, S., Horn, Ch., Rachel, R.: Thermovibrio ruber gen. nov., sp. nov., a novel extremely thermophilic chemolithoautotrophic deeply branching bacterial nitrate-reducer. Int. J. System. Evol. Microbiol. 52, 1859-1865 (2002).

Huber, H., Hohn, M.J., Rachel, R., Fuchs, T., Wimmer, V.C. Stetter, K.O.: A New Phylum of Archaea represented by a nano-sized hyperthermophilic symbiont. Nature 417, 63-67 (2002).

Huber, H., Stetter, K.O.: “Thermoplasmatales”. In: The Prokaryotes: An evolving electronic resource for the microbiological community. 3rd edition (M. Dworkin et al., eds.). New York, Springer-Verlag, 2000 (latest update release 31st Jan 2002).

Rachel, R., Wyschkony, I., Riehl, S., Huber, H.: The ultrastructure of Ignicoccus: Evidence for a novel outer membrane and for intracellular budding in an archaeon. Archaea 1, 9-18 (2002).

Huber, H., Burggraf, S., Mayer, T., Wyschkony, I., Biebl, M., Rachel, R., Stetter, K.O.: Ignicoccus gen. nov., a novel genus of hyperthermophilic chemolithoautotrophic archaeon, represented by two species, Ignicoccus islandicus and Ignicoccus pacificus. Int. J. System. Evol. Microbiol. 50, 2093-2100 (2000).

Huber, R., Huber, H., Stetter, K.O.: Towards the ecology of hyperthermophiles: Biotopes, new isolation strategies and novel metabolic properties. FEMS Microbiol. Rev. 24, 615-623 (2000).

Malandrin, L., Huber, H., Bernander, R.: Nucleoid structure and partition in Methanococcus jannaschii: An Archaeon with multiple copies of the chromosome. Genetics 152, 1315-1323 (1999).

Horn, C., Paulmann, B., Kerlen, G., Junker, N., Huber, H.: In vivo observation of cell division of anaerobic hyperthermophiles with a novel high-intensity dark-field thermomicroscope. J. Bact. 181, 5114- 5118 (1999).

Huber, H., Jannasch, H., Rachel, R., Fuchs, T., Stetter, K.O.: Archaeoglobus veneficus sp. nov., a novel facultative chemolithoautotrophic hyperthermophilic sulfite reducer, isolated from abyssal black smokers. System. Appl. Microbiol. 20, 374-380 (1997).

Burggraf, S., Huber, H., Stetter, K.O.: Reclassification of the crenarchaeal orders and families in accordance with 16S ribosomal RNA sequences. Int. J. System. Bacteriol. 47, 657-660 (1997).

Fuchs, T., Huber, H., Burggraf, S., Stetter, K.O.: 16S rDNA-based phylogeny of the archaeal order Sulfolobales and reclassification of Desulfurolobus ambivalens as Acidianus ambivalens comb. nov.. System. Appl. Microbiol. 19, 56-60 (1996).

Fuchs, T., Huber, H., Teiner, K., Burggraf, S., Stetter, K.O.: Metallosphaera prunae, sp. nov., a novel metal-mobilizing archaeum, isolated from a uranium mine in Germany. System Appl. Microbiol. 18, 560-566 (1995).

Huber, H., Huber, R., Lüdemann, H.-D., Stetter, K.O.: Search for hyperthermophilic microorganisms in fluids obtained from the KTB pump test. Scientific Drilling 4, 127-129 (1994).

Drobner, E., Huber, H., Rachel, R., Stetter, K.O.: Thiobacillus plumbophilus spec. nov., a novel galena and hydrogen oxidizer. Arch. Microbiol. 157, 213-217 (1992).

Huber, H., Stetter, K.O.: Thiobacillus cuprinus, sp. nov., a novel facultatively organo-trophic metal- mobilizing bacterium. Appl. Environ. Microbiol. 56, 315-322 (1990).

Drobner, E., Huber, H., Wächtershäuser, G., Rose, D., Stetter, K.O.: Pyrite formation linked with hydrogen evolution under anaerobic conditions. Nature 346, 742-744 (1990).

Drobner, E., Huber, H., Stetter, K.O.: Thiobacillus ferrooxidans, a facultative hydrogen oxidizer. Appl. Environ. Microbiol. 56, 2922-2923 (1990).

Huber, H., Stetter, K.O.: Thiobacillus prosperus, sp. nov., represents a new group of halotolerant metal-mobilizing bacteria isolated from a marine geothermal field. Arch. Microbiol. 151, 479-485 (1989).

Huber, H., Huber, G., Stetter, K.O.: A modified DAPI fluorescence staining procedure suitable for the visualization of lithotrophic bacteria. System. Appl. Microbiol. 6, 105-106 (1985).

Huber, H., Thomm, M., König, H., Thies, G., Stetter, K.O.: Methanococcus thermolitho-trophicus, a novel thermophilic lithotrophic methanogen. Arch. Microbiol. 132, 47-50 (1982).

Stetter, K.O., Thomm, M., Winter, J., Wildgruber, G., Huber, H., Zillig, W., Janekovic, D., König, H., Palm, P., Wunderl, S.: Methanothermus fervidus, sp. nov., a novel extremely thermophilic methanogen isolated from an Icelandic hot spring. Zbl. Bakt. Hyg., I. Abt. Orig. C2, 66-78 (1981).