Publications:



Ayeni J, Varadarajan R, Mukherjee O, Stuart DT, Sprenger F, Campbell SD, Functionally distinct mechanisms for regulating Cdk1 by T14 and Y15 inhibitory phosphorylation during Drosophila imaginal development, Genetics 2013 in press

Lidsky PV, Sprenger F, Lehner CF., Distinct modes of centromere protein dynamics during cell cycle progression in Drosophila S2R+ cells.J Cell Sci. 2013 Aug 13

Pellegrino, Mark W., Gasser, Robin B., Sprenger, Frank, Stetak, Attila, Ha jnal, Alex, The conserved zinc finger protein vab-23 is an essential regulator of epidermal morphogenesis in C. elegans, Developmental Biology (2009), doi:10.1016/j.ydbio.2009.09.036

Zielke, N., Querings, S., Rottig, C., Lehner, C., and Sprenger, F. (2008). The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles. Genes Dev 22(12): 1690-1703.

Ramachandran, V, Matzkies, M, Dienemann, A and Sprenger, F. (2006). Cyclin A degradation employs preferentially used lysines and a cyclin box function other than Cdk1 binding. Cell Cycle, , 6, 171-181

Zielke, N, Querings, S, Grosskortenahaus, R, Reis, T and Sprenger, F. (2006). Molecular dissection of the APC/C inhibitor Rca1 reveals a novel F-box dependent function. EMBO Rep, 7, 1266-1272

Dienemann, A and Sprenger, F (2004). Requirements of Cyclin A for mitosis are independent of its subcellular localization. Curr Biol., 14, 1117-1123

Grosskortenhaus, R. and Sprenger, F. (2002). Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2. Developmental Cell, 2, 29-40

Kaspar, M, Dienemann, A, Schulze, C and Sprenger, F. (2001). Mitotic degradation of Cyclin A is mediated by mediated by multiple and novel destruction signals. Curr Biol. 11(9), 685-690

Foley, E., and Sprenger, F. (2001). Rux is involved in exit from mitosis in Drosophila. Curr Biol 11,151-160

Foley, E., and Sprenger, F., Cyclins: Growing pains for Drosophila, Curr Biol, 10, R665-R667 (2000) .

Niessing, D., Driever, W., Sprenger, F., Taubert, H., Jackle, H., and Rivera-Pomar, R., Homeodomain position 54 specifies transcriptional versus translational control by Bicoid, Mol Cell, 5, 395-401 (2000) .

Foley, E, O'Farrell, P.H., Sprenger, F. (1999). Rux is a cyclin-dependent kinase inhibitor (CKI) specific for mitotic cyclin Cdk complexes. Curr Biol 9:1392-1402.

Su, T. T., Sprenger, F., DiGregorio, P. J., Campbell, S. D., and O'Farrell, P. H. (1998). Exit from mitosis in drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. Genes Dev 12, 1495-503.

Sprenger, F., Yakubovitch, N., and O'Farrell, P. H. (1997). S-phase function of Drosophila cyclin A and its downregulation in G1 phase. Curr Biol 7, 488-499.

Furriols, M., Sprenger, F., and Casanova, J. (1996). Variation in the number of activated torso receptors correlates with differential gene expression. Development 122, 2313-2317.

Baek, K. H., Fabian, J. R., Sprenger, F., Morrison, D. K., and Ambrosio, L. (1996). The activity of D-raf in torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting. Dev Biol 175, 191-204.

Campbell, S. D., Sprenger, F., Edgar, B. A., and O'Farrell, P. H. (1995). Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro. Mol Biol Cell 6, 1333-1347.

Edgar, B. A., Sprenger, F., Duronio, R. J., Leopold, P., and O'Farrell, P. H. (1994). Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. Genes Dev 8, 440-452.

Sprenger, F., Trosclair, M. M., and Morrison, D. K . (1993). Biochemical analysis of torso and D-raf during Drosophila embryogenesis: implications for terminal signal transduction. Mol Cell Biol 13, 1163-1172.

Sprenger, F., and Nüsslein-Volhard, C. (1993). The terminal system of axis determination in the Drosophila embryo. In The Development of Drosophila melanogaster , M. Akam and A. Martinez-Arias, eds. (Plainview, New York: Cold Spring Harbor Laboratory Press), pp. 365-386.

Sprenger, F., and Nusslein-Volhard, C. (1992). Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg. Cell 71, 987-1001.

Dickson, B.,Sprenger, F., Morrison, D., and Hafen, E. (1992). Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360, 600-603.

Dickson, B., Sprenger, F., and Hafen, E. (1992). Prepattern in the developing Drosophila eye revealed by an activated torso--sevenless chimeric receptor. Genes Dev 6, 2327-2339.

Sprenger, F., Stevens, L. M., and Nusslein-Volhard, C. (1989). The Drosophila gene torso encodes a putative receptor tyrosine kinase. Nature 338, 478-483.

 

Book Chapters

Sprenger, F., and Nüsslein-Volhard, C. (1993). The terminal system of axis determination in the Drosophila embryo.
In:The Development of Drosophila melanogaster, M. Akam and A. Martinez-Arias, eds. (Plainview, New York: Cold Spring Harbor Laboratory Press), pp. 365-386.

Klymkowsky, W. M., Christian, E., Ham, R. G., Plummer, D. J., and Sprenger, F. (1987). Giant axonal neuropathy mutations, intermediate filaments and cellular metabolism.
In: Intrinsic determinants of neuronal form and function, R. Lasek and M. Black, eds. (New York: Alan Liss,), pp. 441-459.