Publications:


Pellegrino, Mark W., Gasser, Robin B., Sprenger, Frank, Stetak, Attila, Ha jnal, Alex, The conserved zinc finger protein vab-23 is an essential regulator of epidermal morphogenesis in C. elegans, Developmental Biology (2009), doi:10.1016/j.ydbio.2009.09.036

Zielke, N., Querings, S., Rottig, C., Lehner, C., and Sprenger, F. (2008). The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles. Genes Dev 22(12): 1690-1703.

Ramachandran, V, Matzkies, M, Dienemann, A and Sprenger, F. (2006). Cyclin A degradation employs preferentially used lysines and a cyclin box function other than Cdk1 binding. Cell Cycle, , 6, 171-181

Zielke, N, Querings, S, Grosskortenahaus, R, Reis, T and Sprenger, F. (2006). Molecular dissection of the APC/C inhibitor Rca1 reveals a novel F-box dependent function. EMBO Rep, 7, 1266-1272

Dienemann, A and Sprenger, F (2004). Requirements of Cyclin A for mitosis are independent of its subcellular localization. Curr Biol., 14, 1117-1123

Grosskortenhaus, R. and Sprenger, F. (2002). Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2. Developmental Cell, 2, 29-40

Kaspar, M, Dienemann, A, Schulze, C and Sprenger, F. (2001). Mitotic degradation of Cyclin A is mediated by mediated by multiple and novel destruction signals. Curr Biol. 11(9), 685-690

Foley, E., and Sprenger, F. (2001). Rux is involved in exit from mitosis in Drosophila. Curr Biol 11,151-160

Foley, E., and Sprenger, F., Cyclins: Growing pains for Drosophila, Curr Biol, 10, R665-R667 (2000) .

Niessing, D., Driever, W., Sprenger, F., Taubert, H., Jackle, H., and Rivera-Pomar, R., Homeodomain position 54 specifies transcriptional versus translational control by Bicoid, Mol Cell, 5, 395-401 (2000) .

Foley, E, O'Farrell, P.H., Sprenger, F. (1999). Rux is a cyclin-dependent kinase inhibitor (CKI) specific for mitotic cyclin Cdk complexes. Curr Biol 9:1392-1402.

Su, T. T., Sprenger, F., DiGregorio, P. J., Campbell, S. D., and O'Farrell, P. H. (1998). Exit from mitosis in drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. Genes Dev 12, 1495-503.

Sprenger, F., Yakubovitch, N., and O'Farrell, P. H. (1997). S-phase function of Drosophila cyclin A and its downregulation in G1 phase. Curr Biol 7, 488-499.

Furriols, M., Sprenger, F., and Casanova, J. (1996). Variation in the number of activated torso receptors correlates with differential gene expression. Development 122, 2313-2317.

Baek, K. H., Fabian, J. R., Sprenger, F., Morrison, D. K., and Ambrosio, L. (1996). The activity of D-raf in torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting. Dev Biol 175, 191-204.

Campbell, S. D., Sprenger, F., Edgar, B. A., and O'Farrell, P. H. (1995). Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro. Mol Biol Cell 6, 1333-1347.

Edgar, B. A., Sprenger, F., Duronio, R. J., Leopold, P., and O'Farrell, P. H. (1994). Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. Genes Dev 8, 440-452.

Sprenger, F., Trosclair, M. M., and Morrison, D. K . (1993). Biochemical analysis of torso and D-raf during Drosophila embryogenesis: implications for terminal signal transduction. Mol Cell Biol 13, 1163-1172.

Sprenger, F., and Nüsslein-Volhard, C. (1993). The terminal system of axis determination in the Drosophila embryo. In The Development of Drosophila melanogaster , M. Akam and A. Martinez-Arias, eds. (Plainview, New York: Cold Spring Harbor Laboratory Press), pp. 365-386.

Sprenger, F., and Nusslein-Volhard, C. (1992). Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg. Cell 71, 987-1001.

Dickson, B.,Sprenger, F., Morrison, D., and Hafen, E. (1992). Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360, 600-603.

Dickson, B., Sprenger, F., and Hafen, E. (1992). Prepattern in the developing Drosophila eye revealed by an activated torso--sevenless chimeric receptor. Genes Dev 6, 2327-2339.

Sprenger, F., Stevens, L. M., and Nusslein-Volhard, C. (1989). The Drosophila gene torso encodes a putative receptor tyrosine kinase. Nature 338, 478-483.

 

Book Chapters

Sprenger, F., and Nüsslein-Volhard, C. (1993). The terminal system of axis determination in the Drosophila embryo.
In:The Development of Drosophila melanogaster, M. Akam and A. Martinez-Arias, eds. (Plainview, New York: Cold Spring Harbor Laboratory Press), pp. 365-386.

Klymkowsky, W. M., Christian, E., Ham, R. G., Plummer, D. J., and Sprenger, F. (1987). Giant axonal neuropathy mutations, intermediate filaments and cellular metabolism.
In: Intrinsic determinants of neuronal form and function, R. Lasek and M. Black, eds. (New York: Alan Liss,), pp. 441-459.